Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 1374 for “"DDC"”.
-
Commutation Error in Reduced Order Modeling
… data-driven correction reduced order model (DDC-ROM). We compare two filters: the ROM projection, which was originally used to develop the DDC-ROM, and the ROM differential filter, which uses a Helmholtz operator to attenuate the small scales in the input signal. We focus on the following …
-
A Novel Antibiofilm Treatment for Surgical Site Infections
… on SSIs. Repurposed diethyldithiocarbamate (DDC-), a metabolite of the old anti-alcoholic drug Disulfiram, previously showed antibacterial activity against mycobacteria and streptococci in combination with copper ions (Cu2+) but had not been investigated against S. aureus and S. epidermidis …
-
The potential of the superoxide dismutase inhibitor, diethyldithiocarbamate as an adjuvant to radiotherapy
… effect by DOC. The inhibition of SOD by DDC was confirmed in a murine rhabdomyosarcoma, and it was shown that this inhibition can be maintained for up to twenty-four hours after DDC administration. It was hypothesised that there was a potential for the radioprotective effect of DDC to be …
-
Cross-Validation of Data-Driven Correction Reduced Order Modeling
… a data-driven correction reduced order model (DDC-ROM) for numerical simulation of fluid flows. The general DDC-ROM involves two stages: (1) we apply ROM filtering (such as ROM projection) to the full order model (FOM) and construct the filtered ROM (F-ROM). (2) We use data-driven modeling to …
-
Μελέτη της έκφρασης και ρύθμισης της L-Dopa Αποκαρβοξυλάσης σε Bιοχημικούς μηχανισμούς Νευροεκφυλισμού
… αύξηση και στα επίπεδα έκφρασης του mRNA της DDC (Lotsios et al. 2023). Για την επίτευξη αυτού του στόχου επιλέχθηκαν δύο κυτταρικές σειρές, οι CHO και CHO-DDC. Τα κύτταρα CHO αποτελούν μοντέλα έρευνας για τη δράση των κατεχολαμινών, καθώς δεν εκφράζουν τις πρωτεΐνες-μεταφορείς τους (Costello …
-
The Impact of a Leadership Development Program on Participants’ Practice: A Case Study of the Development Dynamics Course Organized by Caritas India
… one LDP, the Development Dynamics Course (DDC) offered every year by Caritas India. Caritas India is a large-scale, faith-based, nonprofit organization operating in all states of India that offers the DDC annually for newly appointed leaders of the Catholic church’s social wing.</p> <p>This …
-
Biochemical Studies of Aromatic Amino Acid Decarboxylases and Acetaldehyde Synthases
… 4-dihydroxyphenylalanine (L-dopa) decarboxylase (DDC) is a model enzyme we use as a reference because the structures and functions of DDC are relatively well established. We previously identified two annotated DDC-like proteins from Drosophila indeed catalyzing a decarboxylation-oxidative …
-
Dynamic Discrete Choice Estimation using Reinforcement Learning with Applications in Online Food Markets
Dynamic Discrete Choice (DDC) models are widely used to analyze sequential decision-making in economics and marketing. However, their estimation remains computationally challenging, especially as state spaces expand, limiting their application to large-scale consumer datasets. This thesis develops …
-
In vitro investigation of the anticancer activity and molecular mechanisms of action of albumin nano-encapsulated copper/zinc diethyldithiocarbamate in human pancreatic cancer cells
… ions to form copper diethyldithiocarbamate (Cu(DDC)₂) or zinc diethyldithiocarbamate (Zn(DDC)₂). However, the clinical anticancer application of DSF is hindered by a short plasma half-life (<4 minutes) and bioavailability challenges from separate Cu/Zn supplementation. To address these …
-
Big data value creation : an entanglement of capabilities view-findings from PLS-SEM and fsQCA
… (BDAC), Distinct Dynamic Capabilities (DDC) and Firm Performance (FPer). This research therefore closes the gap between Information Systems (IS) and Strategic Management (SM) research. A higher-order reflective structural model was developed and assessed with 155 online survey responses. …
-
Efectividad de los diferentes programas de tamización en el diagnóstico de displasia del desarrollo de la cadera antes de las 8 semanas de edad: revisión sistemática de literatura
… La displasia del desarrollo de la cadera (DDC) es una patología que de no ser diagnosticada y tratada a tiempo se asocia con complicaciones y morbilidad a largo plazo, incluidas las alteraciones de la marcha, necesidad de intervenciones complejas para corrección de secuelas, dolor crónico e …
-
Time-Varying Frequency Selective IQ Imbalance Estimation and Compensation
Direct-Down Conversion (DDC) principle based transceiver architectures are of interest to meet the diverse needs of present and future wireless systems. DDC transceivers have a simple structure with fewer analog components and offer low-cost, flexible and multi-standard solutions. However, DDC …
-
The epigenetics and role of Dopa Decarboxylase in heart development
… on the parent-of-origin of that allele. The Ddc_exonla gene transcript is under the control of genomic imprinting in the developing and neonatal mouse heart with transcription occurring solely on the paternally inherited allele, with the maternally inherited allele epigenetically silenced. In …
-
High Hill Yak Cheese Production in Nepal: An Analysis of Privatization Policy Incorporating the Impacts of Market Failures for Agro-Industries in Developing Countries
… sectors. The Dairy Development Corporation (DDC) of Nepal produces yak cheese. The DDC's mandate is to provide a "fair" price to consumers and producers. Private producers of cheese have emerged in recent years. Milk shed structures include: single DDC factories, single private factories, …
-
Simulating biochemical physics with computers
… to investigate the role of dopa decarboxylase (DDC) in the catalysis of converting anti-Parkinson drug L-dopa into dopamine. By means of combined QM/MM potentials in MD simulations, we first analyze the factors contributing to the tautomeric equilibrium of an intramolecular proton transfer in …
-
Application of continuous improvement methodologies and techniques in the Drug Design Cycle
… specifically within the Drug Design Cycle (DDC). This is driven by the fact that the average development time for a drug is 10-15 years and drug discovery comprises 3-6 years of this. The DDC process is the main iterative drug discovery process for designing a compound, synthesizing it, and …
-
Development of the Strain-To-Fracture Test to Study Ductility-Dip Cracking in Austenitic Alloys
… testing technique for ductility-dip cracking (DDC) and other elevated temperature cracking phenomenon. Samples are tested over a range of temperature and strain, producing temperature-strain cracking envelopes. Threshold strain for fracture (Emin) and the ductility-dip temperature range (DTR) …
-
THE DNA DAMAGE CHECKPOINT REGULATES MISMATCH REPAIR COMPLEXES DURING SINGLE STRAND ANNEALING PATHWAY
… to DSBs by activating the DNA damage checkpoint (DDC), a surveillance network essential for coordinating a multifaceted response to DNA lesions. Each DSB repair pathway must be coordinated with a series of signalling responses that either halt cell division or cause cell death or adaptation to …
-
Toxicological and Pharmacological Studies on Amide Derivatives of 5-Methoxymethyl-2'-Deoxycytidine
… was determined using CEM cells. Dideoxycytidine (ddC) was used as a positive control drug. At a concentration of 0.5 μM, ddC increased the doubling time of the cells, from the fourth day onward. MMdCyd and But-MMdCyd did not alter the doubling time of the cells up to 2000 μM (highest concentration …
-
Investigation of Weldability in High-Cr Ni-base Filler Metals
… their susceptibility to ductility dip cracking (DDC) using the strain to fracture test at 950 C. Alloys 690NB and 52MSS-E were found to have an equivalent threshold strain of 8% for DDC to occur, indicating similar resistance to DDC. Alloy 52i-B was found to have a threshold strain of 14% …
Page 1 of 69