Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 93 for “"DCE"”.
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A distributed computing environment (DCE) based object request broker
… of a compiler which maps CORBA objects to DCE remote procedure calls. Our objective is to investigate the operation of a distributed object implementation and in particular the performance which can be achieved by a DCE-based Object Request Broker which is CORBA compliant.
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Measurement of The Vascular Input Function In Mice For Dce-Mri
DCE-MRI is an important technique in the study of small animal cancer models because its sensitivity to vascular changes opens the possibility of quantitative assessment of early therapeutic response. However, extraction of physiologically descriptive parameters from DCE-MRI data relies upon …
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Characterization of Cardiomyopathy in a Mouse Model of Duchenne Muscular Dystrophy (DMD) Using Echocardiography, DCE-CT, and PET-FDG
… dynamic contrast-enhanced computed tomography (DCE-CT), positron emission tomography-fluorodeoxyglucose (PET-FDG), echocardiography, and traditional histology to longitudinally assess disease progression and degree of cardiomyopathy in a murine model of DMD (mdx:utrn-/-). No significant changes …
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Characterization of Biomaterials for Regenerative Medicine via Computational Fluid Flow Analysis of Dynamic Contrast Enhanced – Magnetic Resonance Imaging (DCE-MRI) Images
… Contrast Enhanced – Magnetic Resonance Imaging (DCE-MRI) and computational analysis of the images via MATLAB. The analysis was utilized to analyze the fluid flow through several different biomaterial types, allowing for observational comparison between biomaterial groups. Overall, this method for …
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Improved Techniques For Acquisition and Analysis of Dynamic Contrast-Enhanced Magnetic Resonance Imaging For Detecting Vascular Permeability In The Central Nervous System
… contrast-enhanced magnetic resonance imaging (DCE-MRI) is a noninvasive technique for quantitative assessment of the integrity of blood-brain barrier and blood-spinal cord barrier (BSCB) in the presence of central nervous system pathologies. However, the results of DCE-MRI show substantial …
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Does changing the way a discrete choice experiment (DCE) is presented to respondents affect results? An investigation in the context of health using between-subject designs
Discrete choice experiments (DCEs) are a popular stated preference technique used in health. A major challenge in health related DCEs is that they often involve terminology and concepts that may be unfamiliar to respondent. Therefore, it is important for DCEs to include explanations of the concepts …
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Quantification Of Vascular Parametric Indices Using Dynamic Contrast-Enhanced Magnetic Resonance Imaging
… contrast-enhanced magnetic resonance imaging (DCE-MRI) is a non-invasive method used to evaluate the biological activity in early clinical trials of novel drugs targeting the tumor vasculature using gadolinium-DTPA (Gd) as a contrast agent. However, it has some limitations, such as …
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Dynamic Contrast-Enhanced MRI and Diffusion-Weighted MRI for the Diagnosis of Bladder Cancer
… abilities of 3T dynamic contrast-enhanced MRI (DCE-MRI) and diffusion-weighted MRI (DWI) to improve the detection and staging and to enable the prediction of chemotherapeutic response in bladder cancer. A total of fifty-three patients were enrolled in the study. Different inclusion criteria were …
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Assessment of Intrinsic Bioremediation at a PCE Contaminated Site
… partial reductive dechlorination to cis-1,2-DCE and possible anaerobic oxidation of cis-1,2-DCE and VC to CO₂. Microcosms were designed to further evaluate the extent of microbial degradation of the chlorinated ethenes at Site 12 and to provide concentration versus time data for the …
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Mass Spectrometric Analysis of Tyrosine Metabolic Enzymes
… tautomerase (DCT), dopachrome conversion enzyme (DCE) and α-methyldopa resistant protein (AMD) fall into the category of the less characterized enzymes. Dopachrome is a pivotal intermediate in melanogenesis. Mammalian DCT and insect DCE both use dopachrome as a substrate. DCE catalyzes a …
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Methods for the Prediction of Osteoradionecrosis resulting from Head and Neck Cancer Radiation Therapy
… contrast enhanced magnetic resonance imaging (DCE-MRI), and the change in pre- and post-RT DCE-MRI. In the first project, several machine learning and deep learning methods were compared to predict binary ORN status based on treatment dose. This project found that the machine learning …
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A Numerical Model (SEAM3D) to Assess the Biotransformation of Chlorinated Ethenes at a TCE/BTEX Contaminated Site
… analysis showed the biotransformation of TCE to DCE, VC, and ethene. A numerical model was developed to simulate and assess the extent to which reductive dechlorination and direct anaerobic oxidation were responsible for the biotransformation of the chlorinated ethenes. Reductive dechlorination …
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Implementation,Validation and Application of an Automated Motion Correction Algorithm in Hepatic Perfusion CT for Image-Guided Radiotherapy
… used to register dynamic contrast enhanced CT (DCE-CT) image series, which consisted of 40 CT volumes acquired sequentially over 2 minutes. Perfusion maps were generated from unregistered and registered DCE-CT scans and compared to determine impact of motion correction on tumour-normal tissue …
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Bioremediation of chlorinated ethanes and ethenes in vertical flow engineered wetland systems
… (1,1-DCA) and cis-1,2-dichloroethene (cis-1,2-DCE) were used as the chemicals of interest. The presence of cis-1,2-DCE inhibited dechlorination of 1,1-DCA but cis-1,2-DCE dechlorination was not affected by the presence of 1,1-DCA. Simulation runs showed that the treatment bed sizing was …
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Towards image registration of dynamic contrast enhanced MRI using deep learning
Dynamic contrast enhanced (DCE)-MRI is a quantitative imaging technique used to monitor microvascular perfusion. It involves rapidly acquiring multiple T1-weighted images over a few minutes whilst injecting a contrast agent, which causes a rapid increase in image intensity. Each type of tissue …
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The development and piloting of a discrete choice experiment to measure the support preferences of people with chronic respiratory diseases in Ireland
… and piloting of a discrete choice experiment (DCE). Methods: Early work in the thesis identified and explored eight frameworks for SMS of chronic disease developed by national/state level health systems in different countries. Subsequently, a qualitative study was conducted with the …
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Combination therapy studies with the vascular disruptive agent combretastatin-a4-phosphate (CA4P)
… flow related dynamic contrast enhanced MRI (DCE-MRI) parameters between different patients and in lesions within patients on the A5B7 study. Increases in CO (mean +14%, p=0.026) occurred after CA4P whilst falls in tumour Ktrans values were seen (mean -25.1%; p=0.011). There was no evidence …
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Heavy-ion double charge exchange reactions as tools for 0bb decays. The 40Ca(18O,18Ne)40Ar reaction at 270 MeV by using MAGNEX
… of heavy-ion induced Double Charge Exchange (DCE) reactions with high accuracy. The basic point is that the initial and nal state of both 0 bb decay and DCE processes are the same. In addition, both processes pass through the same intermediate state and the transition operators have a similar …
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The analysis of dynamic contrast-enhanced magnetic resonance imaging data: treatment effects, sampling rates and repeatability
… contrast-enhanced magnetic resonance imaging (DCE-MRI) data, primarily by means of pharmacokinetic models, in order to yield parameters which reflect the physiological properties of tumours. Historically, these analysis procedures have been complicated by varied sources of error, both …
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Quantification of cardiac magnetic resonance imaging perfusion in the clinical setting at 3T
Dynamic contrast enhanced (DCE) cardiac magnetic resonance imaging (MRI) is well-established as a non-invasive method for qualitatively detecting obstructive coronary artery disease (CAD) which can impair myocardial blood flow and may result in myocardial infarction. Mathematical modelling of …
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