Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"DARC"”.
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The impact of common and rare human genetic variants on erythrocyte invasion by Plasmodium falciparum malaria parasites
… protect against malaria. The Duffy gene encodes DARC (Duffy antigen receptor for chemokines), which is used by both P. vivax and P. knowlesi parasites to invade red blood cells (RBCs). A single nucleotide substitution in the promoter of the gene where erythroid-specific transcription factors bind …
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Dirac R-matrix scattering calculations in support of plasma diagnostics
… out using the relativistic Dirac R-matrix (DARC) and the semi-relativistic Breit-Pauli (BP) R-matrix codes. The results from these calculations, along with the atomic structure data, are incorporated into collisional-radiative model programs. These collisional-radiative models provide great …
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Photoionization of Se Ions for the Determination of Elemental Abundances in Astrophysical Nebulae
… fully relativistic Dirac Atomic R-matrix Code (DARC). These results are also used to improve the accuracy of the National Institute of Standards and Technology tabulated database of atomic structure. The results for each ion are additionally used to examine specific aspects of the measurement …
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High Fat Diet Effects on Erythrophagocytosis and MCP-1 Levels in Mice
… the Duffy antigen receptor for chemokines (DARC). RBCs may play a role in recruiting immune cells to lesions and contribute to the rupture of atherosclerotic plaques. Although exposure to a high fat diet (HFD) has been shown to alter RBC membrane properties, how this physiological change may …
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Using biophysical tools to explore the erythrocyte preferences of the zoonotic malaria parasite Plasmodium knowlesi
… heavily on the interaction between the parasite DARC (Duffy antigen receptor for chemokines) and human Duffy proteins for invasion, and the parasites are also unable to invade human RBCs without the parasite microneme protein NBPXa. I used these different cell types and invasion preferences to …
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Analysis of FY Promoter and Hepatocystis Load in South African Vervet Monkeys (Chlorocebus Aethiops)
There are species of <em>Hepatocystis</em> and <em>Plasmodium</em>, related blood parasites, that enter the cell through a chemokine receptor, coded for by the Duffy antigen/receptor for chemokines in humans, and the FY*0 (FY Null) allele in the promoter of this gene results in the absence of this …