Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"DAPT"”.
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Enhancing knowledge distillation in large language models via domain adaptation
Domain-Adaptive Pre-Training (DAPT) is widely used to improve Large Language Models on specialized domains, yet its interaction with knowledge distillation (KD) remains poorly understood. In particular, intermediate DAPT checkpoints are rarely analyzed, and the evolution of teacher uncertainty …
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Identifying notch-regulated genes using a specific notch signaling inhibitor
… initiating notch signaling, can be inhibited by DAPT. However, DAPT also targets non-Notch substrates, complicating the identification of genes specifically regulated by Notch. To address this limitation, this study employed IMR-1A, a selective Notch pathway inhibitor that disrupts the assembly …
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Bleeding Risk Following Percutaneous Intervention in Patients with Diabetes Prescribed Dual Anti Platelet Therapy
… prolonged dual anti-platelet therapy (DAPT). While DAPT reduces the risk of ischemic events post-PCI, it also increases the risk for bleeding. Whether long-term rates of bleeding differ among patients with and without DM receiving DAPT in real-world practice is unknown. Among patients …
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Μακροχρόνια παρακολούθηση ασθενών μετά από σύγκλειση ωοειδούς τρήματος
… χορήγηση διπλής αντιαιμοπεταλιακής αγωγής (DAPT) μετά από ισχαιμικό εγκεφαλικό επεισόδιο, ακολουθούμενη από εξατομικευμένη αγωγή με ασπιρίνη ή κλοπιδογρέλη, καθώς και DAPT για 3–6 μήνες μετά τη σύγκλειση του PFO για δευτερογενή πρόληψη, ακολουθούμενη από προσαρμοσμένη μονοθεραπεία με …
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Germ lineage specification from a pluripotent primitive ectoderm-like substrate: a role for cell-cell contacts.
… was enhanced at the expense of ectoderm. DAPT is a potent inhibitor of ƴ-secretase, which cleaves a number of protein targets including the adherens junction component E-cadherin. Addition of DAPT to differentiating EPL cells has the opposite effect to SSP, with an increase in ectodermal …
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Data-driven Materials Informatics for Optoelectronics: From Natural Language Processing to Predictive Modelling of TADF Molecules
… language models via domain-adaptative pre-training (DAPT). Three language models, OE- ALBERT, OE-BERT, and OE-RoBERTa, are produced using this approach. They are also fine-tuned to perform tasks of text-classification, question-answering, and text embedding. Chapter 5 details …
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The Neurogenic Capacity of Müller Glia and Synaptic Remodeling in the Mammalian Retina: Implications for Regenerative Therapies
… inhibition of Notch signaling with DAPT led to the upregulation of some additional neuronal genes in ImM10 Müller glia. Together, these results demonstrated a modest neurogenic capacity for Müller glia. A potential barrier for transplantation of these or any stem-like cells for …
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Interrogating regulated intramembrane proteolysis of IGF-1R, and its role in cell migration
… indicates that gamma-secretase inhibition by DAPT (a small molecule gamma-secretase inhibitor) alone does not antagonise IGF-1-induced cell migration. Similarly, the administration of Pitstop alone does not impinge upon IGF-1 induced cell migration. Interestingly, the administration of …
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Hubungan antara makna hidup dengan dimensi kognitif subjective well being mahasiswa Fakultas Psikologi UIN MALIKI Malang angkatan 2010
… subjective well being, cukup bagus. Hal ini dapt dilihat dari data yang diketahui bahwa 38 orang dengan prosentase 79% memiliki dimensi kognitif subjective well being yang tinggi sedangkan yang berada pada kategori sedang sebesar 21% yaitu sebanyak 10 orang dari 48 mahasiswa yang menjadi …
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DEVELOPMENT OF THE LARVAL PERIPHERAL NERVOUS SYSTEM IN THE ASCIDIAN CIONA INTESTINALIS: ROLE OF THE RETINOIC ACID AND FGF/WNT SIGNALLING PATHWAYS AND OF THE POU TRANSCRIPTION FACTORS.
… The Delta/Notch pathway was inhibited both using DAPT that inhibits the –secretase, responsible of the correct functioning of the pathway and electroporing the pFOG::VeSu(H)DBM construct that blocks the pathway activity. Embryos treated showed an abnormal development of epidermic sensorial …