Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"DAP5"”.
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Regulation of HIF-1α during Hypoxia by DAP5-Induced Translation of PHD2
<p>Death associated protein 5 (DAP5) is an atypical isoform of the translation initiation scaffold eukaryotic initiation factors 4GI and II (eIF4GI/II), which recruit mRNAs to ribosomes in mammals. Unlike eIF4GI/II, DAP5 binds eIF2β, a subunit of the eIF2 complex that delivers methionyl-tRNA to …
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Elucidating the Roles of Eukaryotic Initiation Factors Involved in DAP5 Mediated Translation
… on how eIF3d and its direct binding partner DAP5 are able to co-ordinate with each other to drive the cap-dependent but eIF4E independent mechanism of translation of specific mRNA subsets. We present the first known quantitative and mechanistic studies involving the eukaryotic Initiation …
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Direct Recruitment of eIF4GI and/DAP5 to the 5' UTR of a Subset of Human mRNA Drives Their Cap-independent Translation
… and its homolog, Death Associated Protein 5 (DAP5) expression levels, suggesting these factors have a role in cap-independent translation. Despite several evidence pointing towards a link upregulation of eIF4GI and /DAP5 levels during stress conditions, and the cap-independent translation of a …
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The Role of Secondary and Tertiary Structure in the Cap-Independent Translation of FGF-9 and HIF-1-alpha
… as the eIF4G homolog death-associated-protein-5 (DAP5); however, to date, no significant sequence similarity or conserved secondary structure has been proposed as DAP5 or eIF4G binding sites. RNA structure, however, has previously been found to bind initiation factors in viral IRES. Using …