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Showing 1 to 2 of 2 for “"DACT1"”.

  1. Dact Family Molecules In Wnt Signaling In Mouse Development

    … of the mouse. A mouse mutant lacking the Dact1 gene has been constructed. Despite expression of this gene in patterns suggesting roles in somitogenesis and neuronogenesis, Dact1 mutant mice are caudally truncated due to defective mesoderm formation in late gastrulation. Dact1 mutant mice …

    wustl Repository record for Dact Family Molecules In Wnt Signaling In Mouse Development (opens in a new tab)

  2. Novel intracellular signalling regulators of cartilage progenitor cell populations

    … (Dapper antagonist of catenin) were studied. DACT1 and DACT2 are known to be Wnt and TGFβ pathways regulators, but their role in chondrocytes and MSCs has not been described before. Both proteins are present in chondrocytes throughout the osteoarthritic human tissue, including in chondrocytes …

    cambridge Repository record for Novel intracellular signalling regulators of cartilage progenitor cell populations (opens in a new tab)