Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"DAB2"”.
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Membrane binding properties of Disabled-2
Disabled-2 (Dab2) is an adapter protein that interacts with cell membranes and it is involved in several biological processes including endocytosis and platelet aggregation. During endocytosis, the Dab2 phosphotyrosine-binding (PTB) domain mediates protein binding to phosphatidylinositol …
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Disabled-2 regulates platelet heterotypic and homotypic aggregation through sulfatide binding
… and regulators of aggregation. Disabled-2 (Dab2) is a negative regulator of platelet aggregation released from platelet α-granules. Dab2 binds to the αIIbβ3 integrin, through the PTB domain, and blocks fibrin binding to the integrin which serves as the major cause of platelet-platelet …
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Structural basis for sulfatide recognition by Disabled-2
Disabled-2 (Dab2) is an adaptor protein that plays critical roles in various biological processes, including protein endocytosis, platelet activation and aggregation, tumor growth, and development. In platelets, Dab2 associates with membrane sulfatide at the platelet surface, modulating platelet …
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Sulfatides mediate Disabled-2 membrane localization and stability during platelet aggregation
… in platelet aggregation is Disabled-2 (Dab2), a modular protein that is released upon platelet activation to the extracellular platelet surface.3 Dab2 inhibits platelet aggregation through its phosphotyrosine-binding (PTB) domain by competing with fibrinogen for ï ¡IIï ¢3 integrin …
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The Role of Luteal Phase Fallopian Tube Epithelium in High-grade Ovarian Serous Carcinoma
… I demonstrate that disabled homolog 2 (DAB2), an adaptor molecule decreased in SerCa and FTE luteal samples, enhances both GR-mediated transactivation and suppression of NFκB signalling, implicating DAB2 as a crucial determinant of inflammatory signalling and ovarian cancer risk. …
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Genome-wide association study of muscle traits in Icelandic sheep
… gen eru CSF3R, ADAM17, GADD45B, GRID2, SPG11, DAB2, FREM3, GAB1, KLF13, AKAP6, PNN, DOCK1 og TRRAP. GADD45B hefur virkni sem tengist stjórnun á vexti og frumudauða. Það var raðgreint í 11 sýnum, sýnin voru borin saman og borin við genið í viðmiðunarerfðamengi sauðfjár en enginn breytileiki sem …
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Hyperosmotic Stress Enzyme Signaling Modulates Oct4, Nanog, And Rex1 Expression And Induces Prioritized Differentiation Of Murine Embryonic Stem Cells
… of primitive</p> <p>endoderm markers, Lrp2 and Dab2. Transient, sub-lethal stress delivered prior to the</p> <p>start of hanging drop culture was remembered by mESC, suppressing differentiation</p> <p>events slated to occur from 1-6d later. Mesoderm marker, Brachyury, and anterior</p> …
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Computational study of hydro-environmental processes of Poyang Lake, China
Poyang Lake, the largest freshwater lake in China, plays a key role in regulating the hydrology, water quality and ecosystem in the middle reaches of the Yangtze River. Recent industrial development and urbanization in Jiangxi province have driven rapid increase in water consumption and …