Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"D5R"”.
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Synthesis and Evaluation of C-10 Nitrogenated Aporphine Alkaloids at Serotonin and Dopamine Receptors
… receptors suggesting a lack of tolerability at D5R receptors for C10 N substituted aporphines with moderate to low affinity at D1R, thus attaining D1R versus D5R selectivity. Compound 128e was the most potent D1R ligand (Ki = 58 nM) and lacked binding affinity at all other dopamine receptor …
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THE ROLE OF DOPAMINE D3 RECEPTOR IN ALCOHOL ADDICTION AND SCHIZOPHRENIA
… (GPCR), the D1R-like receptors (D1R and D5R) and D2R- like receptors (D2R, D3R and D4R, Seeman et al., 1994). Among dopamine receptors, the dopamine D3 receptor (D3R) has captured the scientific interest because of its restricted distribution in the brain, seemingly related to functions …
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Mutational Analysis to Define the Functional Role of the Third Intracellular Loop of D1-Class Dopaminergic Receptors
… human D1-class dopaminergic receptors (hD1R and hD5R), have been implicated in modulating their subtype-specific functional phenotypes. The importance of the IL3 for Guanine nucleotide-binding protein (G-protein) coupling and specificity has long been acknowledged in the G-protein-coupled receptor …