Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 22 for “"D-Dimer"”.
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Effects of Blood Contamination on Cerebrospinal Fluid Cell Counts, Protein, and D-dimer Concentrations
… cistern, is lower than previously reported. D-dimers are plasminolytic cleavage products formed by the cross-linkage of fibrin by Factor XIIIa. In humans, D-dimer analysis can be used to differentiate iatrogenic from pathologic CNS hemorrhage. An additional objective of this study was to …
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Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis
… pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the …
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Metals and the conformation of fibrin
… XIIIa) catalysed crosslinked plasmin derived D-dimer into apparently symmetrical monomers has been described. The activity is fibrin specific and displays an unusual site specificity for the γ-carboxy terminal domains within the crosslink region. The activity was reported to be potentiated by …
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The D-domain of fibrin : structural and functional studies
… in buffer containing 4 M urea. Fluorescent-D-dimer (f-D-dimer) was isolated from a plasmic digest of fibrin clotted in the presence of 2.45 mM dansyl cadaverine, a fluorescent lysine analogue. Fluorescent-D-monomer was a by-product of f-D-dimer purification, the yield being determined by the …
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Inflammation and haemostasis in the development and progression of peripheral atherosclerotic disease
… molecule-1 (VCAM-1), E-selectin, fibrinogen, D-dimer, tissue plasminogen activator (t-PA), vonWillebrand factor (vWF), factor VII, fibrinopeptide A (FpA) and prothrombin fragments 1+2 (F1+2) were measured at baseline. Valid ABI measurements were available for 1,582 subjects at baseline, for …
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Prevalence of acute deep vein thrombosis in HIV seropositive orthopaedic patients after major surgery at the University teaching hospital, Lusaka.
… DVT is unknown. In addition the benefits of D-dimer screening of patients after major surgery is not emphasized. A total of 42 Patients, 23 (54 %) were HIV negative (control) and 19 (46 %) were HIV positive were recruited by convenient sampling. Prior to surgery demographic and HIV status data …
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Prevalence of acute deep vein thrombosis in HIV seropositive orthopaedic patients after major surgery at the University teaching hospital, Lusaka.
… DVT is unknown. In addition the benefits of D-dimer screening of patients after major surgery is not emphasized. A total of 42 Patients, 23 (54 %) were HIV negative (control) and 19 (46 %) were HIV positive were recruited by convenient sampling. Prior to surgery demographic and HIV status data …
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Biomarcadores relevantes para diagnóstico precoce e prevenção de doenças cardiovasculares.
… protein , homocysteine , fibrinogen , D - dimer , lipoprotein( a), lipoprotein associated phospholipase A2 , apolipoprotein AI / apolipoprotein B , natriuretic peptides and myeloperoxidase are biomarkers nontraditional whose predictive power and clinical application are under discuss ion . …
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Proteases of the neutrophil membrane represent an alternative fibrinolytic pathway to that mediated by plasmin
… by a monoclonal antibody raised against D-dimer. Processing by neutrophils of the end products of plasmic fibrin degradation may have the potential for modulating the immune response as well as compromising the predictive value of tests measuring D-dimer, used as a laboratory marker of a …
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A retrospective review of CTPA confirmed pulmonary emboli in COVID-19 patients admitted to Groote Schuur Hospital, Cape Town
… differences in demographics, comorbidities or D-dimer levels between patients with or without PE. The importance of a high clinical index of suspicion together with the role of CTPA in diagnosing PE in hospitalised COVID-19 patients is emphasised.
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Clinical Profile Of Patients Who Died Of Covid-19 Infection At A Field Hospital In Cape Town
… showed that 77.14% of patients had high D-dimer and 97.7% had high CRP. Conclusions: The CTICC field hospital was the first intermediate care facility in South Africa born out of a time of need. The mortality rate at this field hospital was 5.53%. Further studies should explore the benefits …
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Early Diagnosis of Pulmonary Embolism: Review and Cost-Effectiveness Analysis
… composed of a clinical decision rule (CDR), a D-dimer test (DD), a compression ultrasonography test (CUS), and a computed tomography pulmonary angiography (CT). Strategy 5, composed by a CDR, DD, a CT, a CUS, and an invasive pulmonary angiography (PA) appeared to be a cost-effective method, but …
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Molecular candidates for Blocking the Transmission of Vector-Borne diseases
… Immunoblotting analysis revealed reduced D-Dimer, a fibrin degradation product, in ticks fed on immunocompromised hosts. In addition, ticks fed on immunocompromised hosts exhibit a lower expression of the arthropod HSP70-like molecule that correlated with higher engorgement weights. This …
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척추 수술에서 예방적 항생제 사용의 유용성
… ESR, CRP) and DIC markers (fibrinogen, FDP, D-dimer) were compared until postoperative 2 weeks. The study groups were homogeneous regarding age, sex, body mass index, estimated blood loss, diabetes mellitus, smoking, diagnoses, baseline laboratory values, and type of surgery including …
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A Prospective, Descriptive Study Evaluating The Evolution Of Covid-19 Associated Coagulopathy In Mechanically Ventilated, Critically-Ill Patients Using Standard Laboratory Coagulation Studies And Thromboelastography
… 92.5% of patients. All patients had elevated D-dimer and fibrinogen levels, prolonged prothrombin times (PT), normal platelet counts and activated partial thromboplastin times (aPTT). No significant differences in laboratory coagulation studies and TEG analysis were noted between survivors and …
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Analysis about efficacy of prophylactic antibiotic therapy for spinal surgery according to its administration period
… 표지자인 섬유소원(fibrinogen), 섬유소 분절물(FDP), D- 이합체(D-dimer)를 반복 확인하였다. 결과 : 각 그룹은 환자의 나이, 성별, 체질량 지수, 예상 출혈량, 당뇨 유무, 흡연 유무, 수술 진단, 수술 전 혈액학적 검사 수치, 수술 술기 등에 있어서 차이를 보이지 않았다. 총 11 례의 환자에서 절개 부위 감염이 발생하였고(7.3%), 총 4 례의 환자에서 장기/강 부위 감염이 발생하였다(2.6%). 각 그룹 간 감염의 발생에 있어서 통계학적으로 유의한 차이는 보이지 않았다(P=0.625, …
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MULTISYSTEM INFLAMMATORY SYNDROME IN CHILDREN:LONGITUDINAL BODY COMPOSITION ASSESSMENT, INFLAMMATORY MARKERS, AND FATTY ACIDS PROFILE
… and erythrocyte sedimentation rate (ESR)and d-dimer, as well as a positive correlation between DHA and ferritin. Overall, the MIS-C children had a favourable disease course. However, nutritional status and loss of body weight should always be monitored in this type of disease during …
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Φλεβική, θρομβοεμβολική νόσος στην κύηση
… αερισμού – αιμάτωσης (V/Q). Η χρήση του test D-dimer είναι περιορισμένη, καθώς τα επίπεδα του αυξάνονται φυσιολογικά κατά την κύηση. Οι LMWH αποτελούν το φάρμακο εκλογής για την θεραπεία και πρόληψη της ΦΘΝ. Η δοσολογία τους προσαρμόζεται βάσει του σωματικού βάρους και δεν συνιστάται …
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A Comprehensive Profiling of Hemostatic Activation and Thromboinflammatory Biomarkers and Cellular Indices in Predicting Outcomes in Venous Thromboembolism
… patients, thrombin generation markers such as D-dimer, F1+2, and TAT were increased. Combining the cellular indices with thrombin generation parameters amplified the predictive value for clinical outcomes in patients with PE. The relationships between thrombin generation potential, biomarkers, …
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¿ROLE OF ENDOTHELIAL DYSFUNCTION IN THE PATHOGENESIS OF UNPROVOKED VENOUS THROMBOEMBOLISM¿
… recurrence (namely, post thrombotic syndrome, D-dimer levels, and presence of residual venous obstruction). To investigate the presence of constitutive ED, ECFCs obtained from the different subgroups of VTE patients and HDs were characterized by assessing: i) their immunophenotype; ii) their …
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