Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"D-2-HG"”.
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Förster Resonance Energy Transfer-Based Quantification of D-2-Hydroxyglutarate & Locked Nucleic Acid Loop-Mediated Isothermal Amplification Mediated Detection of IDH1-R132 Single Nucleotide Variants in Glioma
… biosensor quantifies D-2-Hydroxyglutarate (D-2-HG), an oncometabolite and surrogate marker of <em>IDH1</em> mutations, while the genotyping panel identifies the specific <em>IDH1</em>-R132 single nucleotide variant (SNV) present. The biosensor’s robust function in biological fluids suggests its …
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<i>PTHR1/SOX9</i> and <i>IDH1/IDH2</i> Relative Expression in Primary Chondrocyte and Chondrosarcoma Cells Under the Synergistic Influence of Inducible Hypoxia and Extracellular Acidosis
… oncometabolite D-2-Hydroxygluterate (D-2-HG). Our colorimetric assay data suggest that D-2-HG concentration levels are 10.5-fold and 6-fold more elevated in JJ012/SW1353 respectively than in the <em>IDH</em> wild type CON5. Our gene expression data indicates that both inducible hypoxia and …