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Showing 1 to 1 of 1 for “"Cytosine inhibition"”.
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Design and synthesis studies of new s-adenosyl-l-methionine analogues
… and synthesize new SAM analogues to inhibit cytosine DNA Methyltransferases in tumor cells. A series of target compounds was designed and synthesized in several steps from the starting material adenosine. The synthesis route has been divided into three parts: introduction of the nitrogen at …