Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 951 for “"Cytometry"”.
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Micro-impedance cytometry
… the achievements of this field, micro-impedance cytometry still suffers from a lack of sensitivity and specificity compared to traditional flow cytometry, which limits the potential commercialization of microfluidic impedance devices. While impedance measurements of beads and cells are well …
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3D material cytometry (3DMaC): High-throughput, high replicate screening of materials using flow cytometry
… methods are lacking. This thesis shows how flow cytometry can be adapted to the study of biomaterials. Flow cytometry allows for the automated collection of a large number of unique events in a short time period and is already widely used for cell analyses. Here, biomaterial, specifically …
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Characterization of Photoacoustic Flow Cytometry Signals
<p>Photoacoustic flow cytometry has been utilized to clinically determine the presence of melanoma circulating tumor cells (CTCs). Further investigation was conducted into the morphology of detection signals and how they could be manipulated to allow for further classification. Novel features were …
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Quantitative phase imaging for blood cytometry
… analysis technique known as Diffraction Phase Cytometry (DPC), which is capable of providing the same information on red blood cells as is provided by current clinical analyzers, while rendering additional, currently unavailable parameters on the 2D and 3D morphology of individual red blood …
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High throughput 3-D tissue cytometry
… development of high throughput 3-D tissue cytometry.and its applications in biomedicine. 3-D tissue cytometry has been developed in our laboratory based on two-photon microscopy (TPM) that is capable of in situ 3-D imaging of tissue up to a volume of several mm3 with subcellular resolution. …
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Intrinsic cytometry based on computational microscopy
… label-free microfluidic platform. This intrinsic cytometry will benefit from the parallel and gentle separation of label-free cells via a microfluidic platform and parallel tracking of multiple cells via a large field-of view microscopy in contrast to the gold standard, flow cytometry, which is …
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Micro fluidic cytometry for analysis of marine microorganisms
… carbon dioxide sequestration. Optical based flow cytometry has proved to be strategically important for the study of marine environments in general and of phytoplankton in particular because it enables rapid, simultaneous quantitative analysis of multiple optical properties of particles. …
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Light field microscopy for 3D imaging flow cytometry
… This has motivated the evolution of flow cytometry, which uses microfluidics to measure the fluorescence and scattering signals of thousands of cells per second, towards imaging flow cytometry, which allows spatial information to be collected at extremely high throughput. However, most …
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Microfabricated fused silica flow chambers for flow cytometry
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Electrical Engineering and Computer Science, 1997.
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Modular Neural Networks for Analysis of Flow Cytometry Data
In predicting environmental hazards or estimating the impact of human activities on the marine ecosystem, scientists have multiplied the need for sample analysis. The classical microscopic approach is time consuming and wastes the talent and intellectual abilities of trained specialists. Therefore, …
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Quantitative Characterization of Conserved Noncoding Regions by Flow Cytometry
… implementation of a novel application of flow cytometry in the quantitative characterization of CNRs. The technique couples fluorescent microscopy localization with flow cytometry distribution and expression level analysis, creating a technique more powerful than either on its own. To optimize …
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Estimation of gene network parameters from imaging cytometry data
Synthetic biology endeavors to forward engineer genetic circuits with novel function. A major inspiration for the field has been the enormous success in the engineering of digital electronic circuits over the past half century. This dissertation approaches synthetic biology from the perspective of …
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Automated Analysis of Flow Cytometry Data for B-Cell Lymphoma
Flow cytometry, a powerful tool for the diagnosis of hematolymphoid malignancies including B-cell lymphomas, is an innovative technique that measures the fluorescence of suspended cells. Traditionally, the method of evaluating the research and clinical study of flow cytometry data is done by the …
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Identification of Human Adrenal Carcinoma Cells Using Photoacoustic Flow Cytometry
… needed in samples using photoacoustic flow cytometry (PAFC). PAFC generates ultrasonic waves when particles under flow absorb laser light. Due to the yellow color in adrenal cancer cells, we demonstrate that cells under flow optimally absorb a laser in blue/indigo color. We also determine …
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Physiological studies on bacterial fermentations using multi-parameter flow cytometry
… of both industrial and clinical interest. Flow cytometry was used throughout this work in order to assess the quality of recombinant Escherichia coli populations present within an agitated bioreactor. It was demonstrated in shake-flask culture that the cells could be grown to moderate cell …
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High throughput 3D optical microscopy : from image cytometry to endomicroscopy
… and can potentially be applied to image cytometry investigation to study cultured cell morphologies with statistical significance comparable to the flow cytometer. The statistical accuracy of this instrument is verified by quantitatively measuring the rare cell populations. Hyperspectral …
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Rapid detemination of antimicrobial susceptibility using gel microdroplets and flow cytometry
Thesis (Ph. D.)--Massachusetts Institute of Technology, Whitaker College of Health Sciences and Technology, 1991.
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Large-area cell-tracking cytometry for biophysical measurements of single cells
… I developed a multiparameter intrinsic cytometry approach which integrates multiple label-free biophysical measurements into a versatile (can combine techniques across domains) and readily extensible (to measure more than two biophysical markers) platform for single cell analysis. The …
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Flow cytometry in the diagnosis and prognosis of canine lymphoma and leukemia
… of prognosis for canine lymphoma by using flow cytometry of lymph node aspirates. Data from one hundred and sixty dogs with confirmed multicentric B-cell lymphoma were used to test the hypothesis that poor patient outcome could be predicted by tumor cells expressing a low level of class II major …
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Compositional heterogeneity within oceanic POM : a study using flow cytometry and mass spectrometry
… mass spectrometry (DT-MS), flow cytometry, and multivariate statistics to the study of marine particulate organic matter (POM) collected from the North Atlantic. DT-MS is an important asset to marine organic geochemistry as a single two minute analysis (with 16 eV, EI+ ionization) …
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