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Showing 1 to 1 of 1 for “"Cytokine priming"”.
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Cytokine priming enables triggering of naive auto-reactive CD8[superscript +]T cells by weak agonist ligands of the TCR
… laboratory has shown that with the homeostatic cytokines IL-7 and IL-15 synergize with IL-21 to induce antigen-independent proliferation of naive CD8[superscript +]T cells. Moreover, this cytokine-driven, antigen-independent proliferation "sensitizes" or "primes" naive CD8[superscript +] T cells …