Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Cytokeratin 19"”.
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Detection of Cytokeratin 19 and 20 in Portal Bloods in Right Colon Cancer Patients
… implications. METHODS: From August to December 1998, we collected portal venous blood(10ml) during curative operations on 20 patients with colon cancer. Cytokeratin(CK) 19 and 20 transcripts were amplified using a reverse trascriptase-PCR assay. As a negative control, 10ml of portal blood from …
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Developing a model to assess the contribution of cytokeratin 19-expressing cells during multipotent stromal cell-induced islet regeneration
… for the ‘signal-receiving cell’. Ductal (CK19+) cells from mice pancreata obtained by purification of live Dolichos Biflorus Agglutinin lectin+ cells and cultured in minimal media supplemented with Untreated, Wnt-activated, or Wnt-inhibited CM demonstrated a significantly increased …
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Prognostic Value of Bone Marrow Micrometastasis Detected by Nnested RT-PCR for Cytokeratin 19 and Mammaglobin in Breast Cancer
… study was to examine the presence of keratin-19 and mammaglobin mRNA of epithelial tumors in bone marrow aspirates obtained from breast cancer patients and its possible correlation with tumor staging and disease free survival. METHODS: Bone marrow samples were obtained from 250 breast cancer …
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Efeito do fumo na expressão proteica da citoqueratina 19 (k19) em células epiteliais da mucosa bucal
Objective: to compare the expression of cytokeratin 19 (K19) in epithelial cells of the oral mucosa of smokers, nonsmokers and former smokers. Methods: samples of epithelium of the oral mucosa of smokers (n=20), non-smokers (n=20) and former smokers (n=20) were collected by mouthwash and processed …
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Zur funktionellen Architektur des Nukleolus in lebenden Zellen
… Analysen von zwei pol I-Untereinheiten (RPA194 und RPA53) durch FRAP in transkriptionell aktiven und inaktiven Nukleoli erlaubten direkte Rückschlüsse auf die Transkriptionsdauer der rRNA-Gene in vivo. Die individuellen pol I-Untereinheiten bewegen sich rasch zwischen Nukleoplasma und …
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Preneoplastic hepatocyte hypothyroidism underlies hepatocellular carcinoma progression
… lesions positive for the progenitor cell marker cytokeratin-19 (KRT-19), which are characterized by a higher proliferative activity compared to KRT-19 negative ones. Accordingly, THRs target genes were strongly down-regulated in KRT-19+ lesions. In rat HCC THRβ1 decrease was not due to …
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Immunohistochemical Markers and Ultrasound Elastography - New Diagnostic Options in the Assessment of Thyroid Nodules // Имунохистохимични маркери и ултразвукова еластография - нови диагностични възможности в уточняването на тиреоидните възли
… на имунохистохимичен панел от Galectin-3, Cytokeratin-19 и HBME1, които се позитивират в различните варианти на папиларния, фоликуларния и анапластичния карцином, както и в лимфни метастази от първичен тиреоиден рак. При съмнение за онкоцитарен тумор към този панел следва да се добави …
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COMPARATIVE PROTEOMICS STUDIES OF SOLUBLE NUCLEAR PROTEINS OF DRUG SUSCEPTIBLE AND RESISTANT HUMAN BREAST CANCER MCF-7 CELLS
… Abundances of cytoskeleton proteins, such as cytokeratin 8, cytokeratin 19, septin 2, and alpha tropomyosin, are altered in common across the three resistant cell lines. MCF-7 cell lines resistant to etoposide and mitoxantrone are more similar in protein abundance changes. Some of the proteins …
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Role of cyclin D1 as an estrogen receptor cofactor and the influence of hypoxia on estrogen receptor regulation, with focus on prognositic and treatment predictive features in breast cancer
… showing changes in morphology, proliferation and cytokeratin 19 expression. The hypoxia induced ER reduction was due to both proteasomal degradation and decreased transcription and active extracellular regulated kinase (ERK1/2)was involved in the transcriptional regulation of ER. Consequently, …
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Hepatitis C Virus-Induced Hepatocellular Carcinoma: Cancer Stem Cell and Gene Therapy
… in excessive expression of a-fetoprotein, cytokeratin-19, c-Myc, and c-Src, and activation of b-catenin pathway in the absence of Wnt ligand. The result presented here implicates a novel cellular internal ribosome entry site (IRES) element in the c-Src mRNA responsible for the …
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Development of New Regeneration Methods in Animal Models with Chronic Tympanic membrane Perforations Using Tissue Engineering Techniques
… The cultured TM cells were immunostained with cytokeratin 19 (CK19), integrin β1 (INGβ1), P63 (epidermal stem cell markers), Ki67 (proliferation marker), and DAPI. Rat models for acute or chronic perforations in TMs were prepared. Chronic perforations were produced by a new method - ‘Choung’s …
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Investigation of a pancreatic derived progenitor cell population for use in regenerative medicine
… included induction of gene expression of albumin,cytokeratin 19 (CK 19) and Hepatic Nuclear Factor-1alpha (HNF-1α).Immunocytochemical analysis confirmed functional differentiation with expression of albumin protein and glycogen storage capacity. Both Thy1.1 sub-populations expressed Pdx-1. …
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Characterization of foetal hepatic cells during rat liver development
… entweder zu Hepatozyten (Prox1 positive Zellen/CK19 negative Zellen) oder zur intrahepatischen Gallengang Epithelzellen (Prox1 negative Zellen/CK19 positive Zellen) entwickeln. Die dritte Zellpopulation (positive Zellen für CK19 und prox1) könnte sich zur beiden Hepatozyten und Gallengang …
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Analisi integrata dell'espressione di geni/microrna in un modello di epatocancerogenesi sperimentale
Hepatocellular carcinoma (HCC) is the fifth most common cancer in the world, accounting for an estimated half million deaths annually, and represents one of the major health problems. Although much is known about the cellular changes that lead to HCC, the molecular pathogenesis of HCC is not yet …