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Showing 1 to 10 of 10 for “"Cytochrome c (cyt c)"”.
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Cytochrome C Oxidation by the Bacterial Photosynthetic Reaction Center From Rhodobacter Sphaeroides
… from Rhodobacter sphaeroides and soluble c-type cytochromes has been studied by redox potentiometry and kinetic absorbance spectroscopy. Under intense continuous illumination, in the presence of excess reactants, the RC turnover rate was seen to depend strongly on the bulk ionic strength. Results …
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Neuronal and Mitochondrial Protection in Chronic Parkinsonism
… dysfunction is an immediate response to cytotoxic-inducing agents or is sustained as a long-term consequence of neuronal death. The purpose of our research was to first validate the chronic mouse model of Parkinson’s disorder (MPD), which has been developed and characterized by our …
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Cytochrome c-DNA and cytochrome c-enzyme interactions for the construction of analytical signal chains
… approaches, the redox properties of the protein cytochrome c (cyt c), which acts as an electron shuttle in the respiratory chain, was utilized to engineer ET chains on electrode surfaces. With the help of the biopolymer DNA, the redox protein assembles into electro active multilayer (ML) systems, …
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Uncovering Regulators of Whole-Body Metabolism by Chemoproteomic Profiling of the Adipocyte Secretome
… and many types of cancers. Whereas white adipocytes efficiently store energy in the form of triglycerides, thermogenic brown and beige adipocytes can dissipate energy into heat. Adipose tissue is now considered an important endocrine organ, and increasing evidence suggests that divergent …
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Non-toxic concentrations of α-synuclein exacerbate Parkinson's disease-like cell death by inducing mitochondrial dysfunction
… that α-syn (30 μM) significantly increased cytosolic Ca2+ levels in a time-dependent manner as well as increasing the levels of the apoptotic mediator, cytochrome c (cyt c). The release of cyt c from the mitochondria into the cytosol is indicative of mitochondrial dysfunction and pore …
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Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells
… content we measured mitochondrial DNA (mtDNA), cytochrome c (Cyt c) and citrate synthase (CS). There was a difference between the two cell types in that the markers were profoundly more increased in PBICs compared to platelets even though they displayed approximately the same levels of increase …
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Charakterisierung des Ladungstransfers von immobilisiertem Cytochrom c
… to measure the transient current. In this work cytochrome c (Cyt c) was chosen as redoxactive protein, because it is a relatively well characterized system. Cyt c was immobilized to goldelectrodes via a self assembled monolayer (SAM) ofa carboxylic terminated thiol. In order to contact a single …
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Optimierte Immobilisierung von Redoxproteinen an funktionale Elektrodenoberflächen für die molekulare Bioelektronik
… The main focus lies on the redox protein cytochrome c (cyt c). The charge transfer behavior of this protein was studied while immobilized on macroscopic, microscopic and nanostructured electrodes. Besides the use of previously reported immobilization strategies, e.g. covalent …
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Ion specific effects on charged interfaces
… electrochemical behavior) of some proteins (BSA, cytochrome c, lysozyme) and of silica-based ordered mesoporours material (OMM) chosen as model systems, was the main purpose of this thesis. In particular, the present work is devoted to reach the following aims: I) To investigate the ion specific …
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Cytochrome C biosensor for the determination of trace level arsenic and cyanide compounds
… this work, an electrochemical method based on a cyt c biosensor has been developed, for the detection of selected arsenic and cyanide compounds. Boron Doped Diamond (BDD) electrode was used as a transducer, onto which cyt c was immobilised and used for direct determination of Prussian blue, …