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Showing 1 to 1 of 1 for “"Cytochrome P450 family, Genus cryptococcus, CYP51"”.
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Comparative structural analysis of cytochrome P450 family CYP51 in the genus Cryptococcus
Cytochrome P450 monooxygenase CYP51 (sterol 14α-demethylase) is a well-known target of the azole drug fluconazole for treating cryptococcosis, a life-threatening fungal infection in immune-compromised patients in poor countries. Studies indicate that mutations in CYP51 confer fluconazole resistance …