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Showing 1 to 20 of 20 for “"Cytochalasin B"”.
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Development of a micromixing system for treatment of ORL 48 microtissues in different concentrations of cytochalasin B
… and successfully applied to mix and dilute Cytochalasin-B in culture media (CB-DMEM, 30.0 μM) with 0.05 % ethanol solutions (diluent) to produce four different concentrations of CB-DMEM (5.3, 10.6, 14.8, and 20.2 μM). The different concentrations of CB-DMEM were applied on to ORL-48 …
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The Effects of Black Widow Spider Venom and Cytochalasin-B on The Release of Acetylcholine From Superior Cervical Ganglia of Rats
Made available in DSpace on 2014-12-10T23:24:32Z (GMT). No. of bitstreams: 1 7405670.pdf: 5928878 bytes, checksum: f646f804f75274fcfea7762e0b2aa560 (MD5) Previous issue date: 1973
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Study of wound healing and the involvement of the cytoskeleton in Vaucheria longicaulis variety macounii
… are treated with the cytoskeleton depolymerizers Cytochalasin B and Oryzalin to determine the role(s) of microfilaments and microtubules in organelle movement and the overall role of the cytoskeleton in the wound healing process. In uncut filaments, cytoplasmic streaming is severely reduced by …
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Sodium channel regulatory mechanisms : current fluctuation analysis on frog skin epithelium
… changes in the number of open channels. After cytochalasin B treatment, lowering the mucosal Na⁺ concentration did not result in the usual compensatory changes in channel densities. There was no prior evidence that cytochalasin B had any actual effect on the F-actin network in the frog skin …
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The role of tubulin in ganglioside-induced ramifications in cultured rat brain microglia
… inhibitors of microtubule, but not by cytochalasin B or latrunculin B, which are inhibitors of actin polymerization. In contrast to these morphological changes, iNOS expression was suppressed by both inhibitors of actin filament and inhibitors of microtubule. These results indicate that …
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Vergleich von in-vitro-Ergebnissen im Mikrokerntest und den klinischen Beobachtungen nach Bestrahlung
… Die Zellteilung der Lymphozyten wurde mittels Cytochalasin B (Cyt B) inhibiert. Ergebnisse: Es konnte keine signifikante Korrelation der in-vitro-Strahlenempfindlichkeit und den Normalgewebsreaktionen beobachtet werden. Des weiteren wurde kein Zusammenhang zwischen der Strahlenempfindlichkeit …
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Einfluß der extrazellulären Ca2+-Konzentration und des Aktinfilamentsystems auf die homophile Interaktion von VE-Cadherin
… zu verändern, wurden die Zellen mit Cytochalasin B, Cytochalasin D und dem Ca2+-Ionophor A 23187 inkubiert. Dabei nahm die Bindungshäufigkeit der Mikroperlen deutlich gegenüber Kontrollbedingungen ab. Es wurde gefolgert, daß ein intaktes Aktinfilamentsystem unmittelbar die Interaktion …
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Vergleich von Mikronukleus- und Chromosomenaberrationstechnik bei der Dokumentation zytogenetischer Schäden in neoadjuvant radio-chemotherapierten Rektumkarzinompatienten
… nach der ersten mitotischen Teilung durch Cytochalasin-B blockiert und der zytogenetische Schaden durch die Anzahl der Mikronuklei in Relation zur Anzahl zweikerniger Lymphozyten bestimmt. Eine signifikante Zunahme chromosomaler Schädigungen durch die Bestrahlung in Abhängigkeit von der …
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Identification And Characterization Of The Hexose Transporters In Rat L6 Myoblasts
… study using a number of different approaches. Cytochalasin B (CB), a potent inhibitor of hexose transport, was first used as a probe for these systems. CB binding studies with whole cells and membrane preparations revealed the presence of two distinct CB binding sites, CB{dollar}sb{lcub}rm …
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Triploid induction in the South African abalone, Haliotis midae
… (pi.) and 33-36 min. pi. respectively. Cytochalasin B (CB) (0.5mg. 1-¹ seawater) and elevated temperature (30 °C) were used as stresses to induce triploidy. CB induced 48.4% polar body 1 and 70.9 % polar body 2 triploid larvae at 20 hrs pi. At 120 hrs pi. induction rates were 55.5% and …
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Endovascular trophoblast cell behavior in normal and abnormal pregnancy
… in vivo with a cytoskeleton-disrupting agent, cytochalasin B. This treatment impaired trophoblast cell invasion at day 12 and induced smaller fetuses at day 20, suggesting the importance of cytoskeleton in trophoblast movement. In conclusion, the results suggest the importance of the use of …
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Modulation of TGFβ-Induced PAI -1 Expression by Changes in Actin Polymerization in Human Mesangial Cells
… by direct inhibition of actin polymerization by Cytochalasin B (CytB) suggesting that the effects of Rho on PAI-1 expression are mediated through the actin cytoskeleton. CytB also inhibited the activity of a PAI-1 promoter. Conversely, stabilization of actin microfïlaments with jaspiakinolide …
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GABA as a Putative Neurotransmitter in the Optic Lobes of the Crab HEMIGRAPSUS NUDUS
… the cytoskeletal elements actin or tubulin as cytochalasin B and colchicine did not effect either process.</p> <p>Results described above establish GABA as a putative neurotransmitter in the optic lobes of the eye of <em>Hemigrapsus nudus. </em></p> <p>Demonstration of the presence of …
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The Interaction of Neisseria Gonorrhoeae with Human Monocytes
… The absence of lysosomal enzyme release and the Cytochalasin B inhibition of colony reduction indicated that killing was the result of intracellular bactericidal activity. Disruption of the monocytes by sonication to release internalized bacteria did not alter the number of viable colony-forming …
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Genomische Instabilität bei der humanen Ovarialtumorzellinie BG-1 durch hormonelle Proliferationsstimulierung
… als durch den Einsatz des Zytokineseinhibitors Cytochalasin B die Auswertung der Mikrokerne auf jene Zellen normiert wurde, die genau eine Zellteilung durchgeführt hatten. Die Ergebnisse machten deutlich, dass die östradiolstimulierten Zellen auf Grund der beschleunigten Proliferation eine …
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Development of a novel cell traction force transducer based on cholesteryl ester liquid crystals. Characterisation, quantification and evaluation of a cholesteryl ester liquid crystal based single cell force transducer system.
… cell attachment. Cell relaxation technique by cytochalasin-B treatment suggested that the attachment and contraction of cells on LLC was due to the contractile activity of actin cytoskeletons that are mediated by focal adhesions. The staining experiments showed that cells consistently expressed …
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Functional analysis of ICAM-1 : LFA-1 interaction in cell adhesion
… as judged by the inhibitory effect of cytochalasin B. PMA induced adhesion could not be inhibited by sICAM-1, suggesting that this cell adhesion was mediated by low affinity ICAM-1:LFA-1interaction. In contrast, Mn++ induced adhesion seemed to be mediated by an increase in the affinity …
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Erythrocyte deformability as assessed by nuclepore filters
… denaturing compounds colchicine, vinblastine and cytochalasin B to produce deformability alterations were tested using the filtration technique. No consistently measurable differences in deformability were seen between the incubated cells and the control cells. The results imply that cell ATP …
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Host-Parasite Interrelations: Bacterial Adherence to and Invasion of Epithelial Cells
… for EIEC. The microfilament disrupting agent cytochalasin B (CB) reduced EIEC invasion by more than 50-fold. Furthermore, CB depressed the extent of EIEC invasion of PEG-treated and untreated HeLa cells to equivalent levels. The large, multinucleated HeLa cells generated by PEG treatment …
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Computational modeling of tumor cell growth as a function of nutrient dynamics guided by time-resolved microscopy
The varying and extreme nutrient conditions found in the tumor microenvironment force reprogramming of metabolism in tumor cells. This metabolic reprogramming has been identified as a hallmark of cancer. This dissertation focuses on the development and validation of an experimental-mathematical …