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Showing 1 to 3 of 3 for “"Cystagon"”.
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Characterisation of cysteamine prodrugs for the treatment of cystinosis and evaluation of liquid fill technology.
… administration of the aminothiol, cysteamine (Cystagon(TM)), but this has an offensive taste and smell, can cause vomiting and its metabolites are excreted from the body via breath (halitosis) and sweat, which can cause poor patient compliance. The main research aim was to characterise two …
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Formulation studies on cysteamine for the treatment of nephropathic cystinosis.
… administration of the aminothiol, cysteamine (Cystagon TM), which possesses an offensive taste and smell. The oral form frequently causes emesis and should be administered every six hours to be maximally effective. The topical eye-drop treatment requires hourly application to be most effective. …
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The design and synthesis of novel pro-drugs for the treatment of nephropathic cystinosis.
… have shown the ability of the drug cysteamine (Cystagon®) to lower cystine accumulation within cells resulting in reduced organ and tissue damage. Cysteamine therapy however, is associated with a number of side effects involving the gastrointestinal tract and the central nervous system. Most of …