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Showing 1 to 3 of 3 for “"Cyclin Y"”.
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Functional Analysis Of A Highly Conserved Cyclin, Cyclin Y, In Drosophila Melanogaster
<p>Cyclin Y is a highly conserved member of the Cyclin superfamily of proteins. In Drosophila the Cyclin Y gene (CycY) is required for progression through several stages of development but the specific pathways that Cyclin Y belongs to and that account for its requirement are not known. Studies in …
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Determination Of The Essential Functions Of A Conserved Cyclin, Cyclin Y, In Drosophila
… encodes a member of a highly conserved family of cyclins, the Y type cyclins, which have not been functionally characterized in any organism. Here I report the generation and phenotypic characterization of a null mutant of <i>CG14939</i>, which we rename <i>Cyclin Y</i> (<i>CycY</i>). I show that …
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Investigating the regulation of the PCTAIRE-1 protein kinase : a new target of AMP-activated protein kinase and beyond?
… studying its regulation. I have also validated cyclin Y as a binder and robust activator of PCTK1. I next characterised phospho-antibodies directed against key regulatory residues on PCTK1, including the activation/T-loop. This work has given a fundamental basis for PCTK1 characterisation, and …