Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 10 of 10 for “"Cyclic nucleotide-gated channels"”.
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Structural Insights into Ion Selectivity and Calcium Blockage in Cyclic Nucleotide Gated Channels
Cyclic nucleotides-gated (CNG) channels play an essential role in the visual and olfactory sensory systems and are ubiquitously expressed in a variety of neuronal and non neuronal cells. Details of their underlying ion selectivity properties are still not fully understood and a matter of debate in …
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The Role of Arabidopsis thaliana Cyclic Nucleotide-Gated Channels 2, 6, and 19 in Extracellular ATP Signalling
… membrane (PM) eATP receptors DOES NOT RESPOND TO NUCLEOTIDES1 (DORN1/P2K1) and DORN2/P2K2 have been identified in Arabidopsis thaliana in the past decade. The perception of eATP leads to downstream changes of secondary messengers, including cytosolic free calcium ([Ca2+]cyt) increase, reactive …
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Testing the Role of Cyclic Nucleotides in Regulating Ion Channels Essential to Pollen Fertility
It is unknown if plant cyclic nucleotide gated channels (CNGCs) are activated by cyclic nucleotide monophosphates (cNMPs, e.g. cAMP or cGMP), or even if cNMPs are present at physiologically significant levels in plants. cNMP presence in growing A.thaliana pollen tubes was visualized using …
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Genetic analysis of cGMP-dependent chemosensory signal transduction pathways in the detection of bacterial metabolites by C. elegans
… for the pathway, including a subunit for cyclic nucleotide-gated channels, CNG-2, and a cGMP-dependent kinase, EGL-4. We show that while CNG-2 induces daf-7 expression in a calcium-dependent manner, EGL-4 likely works in a calcium-independent manner to regulate daf-7 expression. Our data …
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Manipulation of second messengers by ectopic expression of receptors in transgenic Drosophila
… selective manipulation of the second messengers cyclic GMP (cGMP), cyclic AMP (cAMP) and calcium (Ca2+) in the renal (Malpighian) tubule of the genetic model organism, Drosophila melanogaster. The importance of the second messengers cGMP, cAMP and Ca2+ in control of fluid transport makes the …
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Structure-Function Analysis of Insect Olfactory Receptors
… intracellular second messengers and opening of cyclic nucleotide-gated channels (CNG; Buck and Axel, 1991; Colbert et al., 1997; Firestein et al., 1991; Nakamura and Gold, 1987; Troemel et ii al., 1995). Insect ORs lack similarity to GPCRs (Benton et al., 2006; Vosshall et al., 1999), and we …