Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"Cyclic Olefin Copolymer"”.
-
3D cyclic olefin copolymer (COC) microfluidic chip fabrication using hot embossing method for cell culture platform
… have been transferred from PDMS to a platform in cyclic olefin copolymer (COC) which has advantages in terms of hydrophobicity, production by the more commercially-viable hot embossing technique, and amenability to surface treatments. Here the fabrication process is described and the new systems …
-
DEVELOPMENT OF FREE-LABEL SENSING IN PLASTIC MICROFLUIDIC PLATFORMS USING PULSED STREAMING POTENTIALS (PSP)
… (PAA) and polyethylene glycol acrylate (PEGA) on cyclic olefin copolymer microchannels, as well as adsorption of nanospheres on COC-PEGA channels.
-
Laser Processing of Metals and Polymers
… films of niobium nitride and organic material (cyclic olefin copolymer).</p> <p>The treated materials were examined by scanning electron microscopy (SEM), electron probe microanalysis (EPMA), atomic force microscopy (AFM), high resolution optical microscopy, surface profilometry. Fourier …
-
Enhancing Micro Free Flow Electrophoresis: Detection, Application, And Fabrication
… technique for hot embossing µFFE devices in cyclic olefin copolymer (COC) with the goal of expanding µFFE’s use in analytical workflows. A new laser alignment for LIF was explored, focusing the laser light through the side of the device instead of spreading it into a line and reflecting it …
-
Microfluidic platforms for protein crystallization and in situ X-ray analysis
… control layer are replaced with thin layers of cyclic olefin copolymer (COC). This hybrid COC-PDMS device architecture takes advantage of the low X-ray scattering cross-section of organic polymers such as COC while minimizing the path-length of the more strongly scattering silicon-based PDMS. …
-
Polymeric microfluidic platform combined with Fourier Transform infrared imaging to explore biomolecular reactions
… We developed polymeric MCFMs using a low-cost cyclic olefin copolymer (COC) that is physically and spectrally biocompatible, and well suited for microfabrication. We used strong covalent bonding between device layers to enable the high flow rates needed to probe sub-millisecond reactions and …
-
Microwave Overlay Capacitor Fabrication on Printed Circuit Boards
… two types of polymer. An existing recipe using cyclic olefin copolymer (COC) was adapted for spray coating, while a new recipe based on poly methyl methacrylate (PMMA) was designed for spray coating. To complete the capacitors, a metal layer was deposited using a Voltera V-One printer with the …
-
Single-molecule detection of molecular beacons generated from LDR on thermoplastic microfluidic device for bioanalysis
… FRET pairs (spFRET). The LDR was performed in a Cyclic Olefin Copolymer (COC) microfluidic device equipped with 2 or 20 thermal cycles in a continuous flow format. Single-molecule photon bursts from the resulting rMBs were detected on-chip and registered using a laser-induced fluorescence (LIF) …
-
Polymer-Based Microfluidic Devices for High Throughput Single Molecule Detection: Applications in Biological and Drug Discovery
… biochemical assay was investigated using a novel cyclic olefin copolymer (COC) planar waveguide embedded in PMMA and situated orthogonal to multiple fluidic channels. This design allowed for fluorescence detection from multiple fluidic channels using evanescent excitation and a wide FoV …
-
A Plastic-Based Thick-Film Li-Ion Microbattery for Autonomous Microsensors
… with microelectronic fabrication processes. A Cyclic Olefin Copolymer (COC)-film was used as both the substrate and primary sealing materials, and patterned metal foils were used as the current collectors. A liquid-state electrolyte and Celgard separator films were used in the microbatteries. …
-
Fully Integrated Modular and Mixed-Scale Systems for Processing the Molecular Cargo of Liquid Biopsy Markers
… thermoplastic valves using an elastomeric cyclic olefin copolymer membrane were characterized. The membrane/substrate bond was demonstrated to withstand high burst pressure (~10 psi or ~50 psi) using a novel in situ bonding method. These valves were integrated into three different systems …