Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Cx26"”.
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Identification of Connexins in Facilitating Neuron-Satellite Glial Cell Signaling in Trigeminal Ganglia
… the formation of gap junction plaques by Cx26 was observed between neurons and satellite glial cells. In other studies, a model of acute-sensitization was used to simulate the significant comorbitities between rhinosinusitus and migraine. In this model, increased gap junction signaling …
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RegulationofGap Junction Protein,Connexins in Immortalized Human Keratinocytes Cells(HaCaTcells)
… showed more increased expression of Cx43 and Cx26 than retroauricular skins. In another study for making in vitro 3 dimensional model of cholesteatomas, there was some difference of epithelial characteristics between a spontaneously immortalized epidermal cell line (HaCaT) and cultured …
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The Characterization of Cx31 in Keratinocytes and its Link to Erythrokeratodermia Variabilis et Progressiva
… of Cx31 and its interplay with co-expressed Cx26, Cx30 and Cx43 in rat epidermal keratinocytes. We demonstrated that the apparent half-life of Cx31 was extended compared to Cx43, and that Cx31 gap junctions persisted longer at the cell surface. In REKs, Cx31 gap junctions were dynamic and the …
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FATE OF Cx43 IN CARDIAC AND EPIDERMAL TISSUES HARBOURING A DISEASE-LINKED Cx43 MUTANT
… there was a concurrent 75% down-regulation of Cx26 in the skin. Immunohistochemistry revealed a trafficking defect, with a population of Cx43 retained in the Golgi apparatus. Despite the decrease in Cx43, cardiomyocytes from Gjal5* mice show normal dye coupling and synchronous beating. However, …
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Turnover Rate of The Neuronal Connexin Cx36 In Hela Cells
… 3.5 hours in pulse-chase analyses of connexins (Cx26 and Cx43) in tissue culture cells and whole organs. We utilized HaloTag technology to study the turnover rate of Cx36 in transiently transfected HeLa cells. The HaloTag protein forms irreversible covalent bonds with chloroalkane ligands, …
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Investigation of biological macromolecules using atomic force microscope-based techniques
… to visualize the extracellular surface of Cx26 gap junction hemichannels (connexons). AFM topographs reveal pH-dependent structural changes of the extracellular connexon surface in presence of HEPES, an aminosulfonate compound. At low pH (< 6.5), connexons showed a narrow and shallow …