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Showing 1 to 20 of 22 for “"CuA"”.
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Diagnóstico forestal y agroforesal en la subcuenca Cua-Bocaycito, Municipio Cua-Bocay, Jinotega 1994
El municipio Cuá-Bocay tiene una superficie de 4,234 Km', posee un clima tropical húmedo, con una precipitación anual que varía de 2,500 - 3,000 mm. los suelos generalmente son franco arenoso o franco arcillolimoso. El objetivo del estudio fue realizar un diagnóstico del estado actual del recurso …
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A biosynthetic approach to understanding the assembly of CuA centers
… transfer throughout all domains of life. CuA is a unique dinuclear, mixed-valence and valence delocalized copper center, which catalyzes remarkably efficient electron transfer under the low driving forces experienced at the termini of electron transport chains. Historically, CuA centers …
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Designing Novel Blue Copper and Purple CuA Centers in Azurin With Natural and Unnatural Amino Acids
Finally, loop-directed mutagenesis was used to incorporate a 2Fe-2S cluster binding loop from human ferrochelatase into azurin. Preliminary iron binding studies indicate the assembly of a 4Fe-4S or a 2Fe-2S iron sulfur cluster.
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Probing the roles of metal binding ligands in cupredoxins: incorporating nonproteinogenic amino acids into azurin and CuA Azurin
Item withdrawn by Mark Zulauf (zulauf@illinois.edu) on 2010-05-13T19:03:20Z Item was in collections: University of Illinois Theses & Dissertations (ID: 1) No. of bitstreams: 1 Clark_Kevin.pdf: 14900477 bytes, checksum: 901cc6f1c2f90be4a62e58094e6f0b6d (MD5)
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Engineering a Purple copper(A) Site Into the Blue Copper Protein Azurin: Construction, Spectroscopy, and Metal Substitution Studies
Metal substitution studies of azurin-CuA have been performed using various metal ions (i.e., Hg2+, Ag+, Cu +, Cd+, Rh2+, Au+, Co 2+, and Ni2+). Metal binding was determined by electronic absorption and electrospray mass spectrometry. The results obtained from theses studies indicate that there are …
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THE REGULATION OF THE INTESTINAL COPPER EXPORTER IS COORDINATED WITH SYSTEMIC COPPER HOMEOSTASIS
… in C. elegans. Moreover, we show that CUA-1, the ATP7A/B homolog in worms, localizes to lysosome-like organelles (gut granules) in the intestine under Cu-overload conditions for Cu detoxification, while Cu-deficiency results in a redistribution of CUA-1 to basolateral membranes for Cu …
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Structural characterization of the two copper proteins nitrous oxide reductase from Pseudomonas stutzeri and laccase Lcc5 from Coprinopsis cinerea
… Domäne, welche ein gemischt-valentes CuA-Zentrum trägt, ähnlich dem der Cytochrom c Oxidase. Diese N2O-Reduktasestrukturen repräsentieren jedoch aerob isoliertes Protein, welches nur aktiv ist, nach einer verlängerten Inkubation mit Reduktionsmitteln. Im Gegensatz hierzu zeigt die …
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Efecto de la fertilización fosfórica sobre el crecimiento y rendimiento de cuatro variedades de frijol común (Phaseolus vulgaris L.)
… respuesta a la aplicación creciente de fósforo, cuatro variedades de frijol común: Cua 88, Compañía 88, Nicaragua 88 y Revolución 79; fueron evaluadas bajo cuatro niveles de P en forma de P2O5; 0, 46, 92,138 kg/ha, utilizando triple superfosfato como fuente de fósforo. El diseño utilizado fue el …
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Campesino Participation in Rural Paraguay: Practical and Theoretical Challenges
In 1997, the community of Guayaki-Cua, Paraguay underwent a dramatic political and social transformation allowing campesinos to take a more active role in decisionmaking processes. This change established safety and security for local residents, and brought about the involvement of the Paraguayan …
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Probing the Roles of Metal Binding Ligands in Cupredoxins: Incorporating Nonproteinogenic Amino Acids Into Azurin and Copper a Azurin
… individual metal ligand residues in azurin and CuA azurin by using EPL to incorporate nonproteinogenic amino acid analogues has been demonstrated. This work has resulted in new insights into the role of the metal ligands and has shaped future metalloprotein engineering efforts.
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Metal Thiolate and Metal Sufide Clusters in Proteins
… with reducing equivalents provided by a CuA site. The cluster is composed of four copper atoms bridged by a central sulfide, with remaining all histidine coordination to the copper atoms. A scaffold protein was selected, and residues were chosen for mutagenesis to create a similar ligand …
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Fine���tuning the reduction potential of Cupredoxin proteins by altering secondary coordination sphere interactions
… to other metal sites. The Em of the dinuclear CuA site in the engineered protein CuA Az was tuned in a similar fashion by altering the hydrogen bonding network around one of the copper ligands. Because > 85 % of the protein is the same between Az with a T1 copper site and CuA Az with a …
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Childhood varicella vaccination: an evaluation of clinical effectiveness, safety and cost effectiveness in Ireland
… (study 3). Lastly, a cost-utility analysis (CUA) was conducted to estimate the cost effectiveness of universal childhood varicella vaccination in Ireland (study 4). Results From a total of 20 systematic reviews, there was clear and consistent evidence that vaccination is very effective at …
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Las raíces simbólicas del teatro de Ricardo Monti : paradigmas simbólicos de lo femenino
… en el campo supranacional. Es ponderable la cua-lidad unitiva de la obra de Monti, en la que el itinerario hacia el símbolo, con claras referencias a doctrinas místicas, fue intensificándose progresivamente, especialmente en la última étapa de su teatro barroco; pero esa intensificación, …
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Study of the Proton Pumping Mechanism of the Aa3-Type Cytochrome C Oxidase
… c are first transferred to a copper center, CuA, which is located on the electrically positive (P) side of the membrane, then transferred through low spin heme a to a binuclear center (high spin heme a3 and CuB) which is the catalytic site of the CcOs. O2 binds to reduced heme a3, which is …
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Energy-efficient systems for information transfer and processing
… benefits of BOA over a conventional uniform ADC (CUA) in a serial link receiver are substantial. Second, a \unit[4]{GS/s}, 4-\mbox{\textrm{bit}} on-chip ADC in a \unit[90]{nm} CMOS process is designed and integrated into a 4 Gb/s serial link receiver to verify the aforementioned analysis. …
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Mental Health Service Utilization Patterns in a School Mental Health Program for High Poverty Communities
Background: Children living in poverty experience high rates of mental health difficulties including high rates of externalizing and internalizing disorders. However, up to 80% of low-income children in need of mental health services do not receive needed services. Given the barriers and lack of …
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Why do allelic variants of the mitochondrial chaperone SCO1 cause clinically heterogeneous forms of disease? A mouse model and proximity ligation study
… the importance of the SCO1-COX16 interaction to CuA site maturation, given that its abundance was greatly reduced in some brain regions and its affinity for SCO1 was attenuated by the M294V substitution. Consistent with these findings, I found that COX16 overexpression was able to partially …
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Occupational Choice and Academic Planning in the Colombia-Venezuela Union of Seventh-day Adventists : a Needs Assessment
… of their adult counterparts.</p> <p>3. CUA Academic Master Plan needs to be re-designed to reflect current and future demands of the labor market.</p> <p>4. Administrative involvement is crucial in securing institutional commitment to the needs-assessment process.</p> <p><em> …
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The synthesis and metal ion catalysed hydrolysis of methyl 4,5-diaminopentanoate
… CuE₂²⁺ + OH⁻ → CuEA⁺ + CH₃OH 1 CuEA⁺ + OH⁻ → CUA₂ + CH₃OH 2 The relative values for the two rate constants obtained (k (CuE₂²⁺) = 2.41ℓmol⁻¹s⁻¹ and k (CuEA⁺) = 0.80ℓmol⁻¹s⁻¹ at 25°C and I = 0.10molℓ⁻¹) can be explained by charge and statistical effects. The value of k(CuEA⁺) was confirmed …
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