Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Cu(I)-catalyzed azide-alkyne cycloaddition"”.
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Serum Stable Carbohydrate-Oligoethyleneamine Copolymers for Nucleic Acid Delivery
… area. Since nucleic acids are bulky macromolecules and unstable in the presence of nucleases, vehicles are required to compact them into nanosized particles, offer protection from degradation in vivo, and release the therapeutic cargo at the desired location. Polycationic vehicles are good …
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Micro- and millifluidic platforms for imaging agent synthesis
Molecular imaging, the non-invasive visualization of cellular and sub-cellular events, holds great promise to improve the basic understanding of biochemical processes and clinical diagnosis of diseases. One widely used molecular imaging technique is positron emission tomography (PET) that is …
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Click chemistry for colloidal assembly
… from the arsenal of click chemistry, called Cu(I)-catalyzed azide alkyne cycloaddition (CuAAC) to develop an approach for directed colloidal assembly. Colloidal crystals are used here as an ideal model system for studying directed self assembly. This study develops a modular approach towards …
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DNA enzymes for peptide-nucleic acid conjugation and for lysine methylation
… 2, a new in vitro selection approach for DNA-catalyzed peptide nucleic acid conjugation is described. This new selection approach uses untethered, free peptide substrates containing an azido group at the N-terminus. Capture of the catalytically active sequences by Cu(I)-catalyzed azide-alkyne …