Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"CtrA"”.
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SciP : a novel inhibitor of CtrA transcriptional activity in Caulobacter crescentus
… crescentus to examine the regulation of CtrA, the essential transcription factor at the core of the Caulobacter cell cycle regulatory network. CtrA regulates the activity of approximately 100 cell cycle genes many of which are critical for cell cycle progression. CtrA activity is …
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Global analysis of the transcriptional regulation of Sinorhizobium meliloti cell cycle progression and study of cell cycle regulation during symbiosis with Medicago sativa
… cycle regulated transcripts might be part of the CtrA and DnaA regulons in S. meiloti, I performed CtrA and DnaA binding motif analysis. To understand the evolutionary significance of these CtrA and DnaA binding motifs, I looked at conservation of these motifs in homologous genes from several …
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Regulation of cell fate asymmetry in Caulobacter crescentus by a complex of two component signaling proteins
… In Caulobacter, the master cell cycle regulator CtrA is selectively activated in swarmer cells, deactivated in stalked cells, and reactivated in predivisional cells. CtrA controls DNA replication, polar morphogenesis and cell division, and its cell-type and cell cycle-specific regulation is …
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Phosphorylation-based control of cellular asymmetry and the cell cycle in Caulobacter crescentus
… of an essential cell cycle regulator called CtrA. This spatial gradient of CtrA phosphorylation enforces replicative asymmetry and couples it to the asymmetric morphogenesis of the daughter cells. I then investigate how CtrA's control of replicative asymmetry relates to the control of …
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Treatment response using CT-based rigidity analysis in an animal model of lytic musculoskeletal lesions subjected to systemic therapy
… of imaging methods in current clinical practice. CTRA provides highly accurate monitoring of metastases progression and treatment through both Ibandronate and Paclitaxel therapies. Using computed tomography (QCT)-based analysis to calculate the load bearing capacity of bone infiltrated with …
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Host-Dependent Expression, Transcriptional Regulation and Protection of Ehrlichia chaffeensis Tandem Repeat Proteins
… expression of E. chaffeensis TRPs, the role of CtrA as a gene expression regulon and the protection mediated by antibodies directed at the molecularly characterized epitopes within the TRs of TRP32, 47 and 120. Our results revealed three novel characteristics of these ehrlichial proteins. First, …
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Mathematical Model of the Cell Cycle Control and Asymmetry Development in Caulobacter crescentus
… that there may be unknown pathway(s) reducing CtrA under starvation conditions, which results in delayed cytokinesis in starved stalked cells. The cell cycle development of Caulobacter is determined by the periodical activation and deactivation of the master regulator CtrA. cdG is an essential …
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Mathematical modeling of molecular mechanisms governing cell cycle progression in Caulobacter crescentus and differentiation of immune system progenitor cells
… for the unknown form of the master regulator, CtrA, in regulating the G1-S transition. Furthermore, we incorporate a nutrient signaling model into the cell cycle model to investigate how Caulobacter responds to nutrient deprivation. We find that regulation of DivK phosphorylation is an …
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The use of molecular diagnostic methods to improve the detection of the common bacterial and viral causes of community acquired meningitis in children in South Africa
… bacterial causes namely: Neisseria meningitidis (ctrA gene), Haemophilus influenzae (hpd gene) and Streptococcus pneumoniae (lytA gene) and viral causes namely: enterovirus (5' UTR), herpes simplex (UL30 gene) and mumps virus (Fusion protein gene). The qPCR assays were carried out on the Biorad …