Global ETD Search
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Showing 1 to 2 of 2 for “"Csl4"”.
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Characterization of The Rna Binding and Rna Degrading Subunits of The Eukaryotic Exosome
… “cap”, the RNA binding proteins Rrp4, Rrp40, and Csl4. I determine that in spite of their structural similarity, they each have a unique essential role. Second, I determine that two of the cap proteins Rrp4 and Rrp40 have a role in bridging subunits of the PH ring of the exosome. The third cap …
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Functions of RNA exosome and tRNA splicing ligase in Mendelian and Infectious diseases
… mutations in the corresponding yeast subunit Csl4, revealed malfunction in the nuclear and cytoplasmic functions of RNA exosome. These two patient-derived mutations are located in functionally redundant domains of Csl4, and each variant partially impaired RNA exosome function by disrupting its …