Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Crystallography, X-Ray"”.
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New Approaches in Nonlinear Analysis and Modeling of Multichannel Signals
… a variety of fields and imaging systems such as Crystallography, X-ray, optical imaging, and astronomical imaging. Although traditional algorithms such as the hybrid input-output (HIO) method, and continuous hybrid input–output (CHIO) are widely used to solve this problem, their reconstruction …
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Optimization and Analysis of Weighted-Window Predictors of Structural Disorder in Proteins
The file named "holladaynathan.pdf" is the primary dissertation file. A supplemental Microsoft Excel file ("hollady_suppl_workbook.xls") is also available.
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Protein Mechanics Through X-Ray Crystallography
… show that cycles of mutagenesis coupled with X-ray crystallography can reveal an anisotropic, distributed pattern of physical interactions in a PDZ domain, PSD-95 PDZ3. This pattern is functionally important and deeply connected to the evolution of PDZ domains in general. Second, we present a …
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Autoinhibition and Chloride Sensing in the WNK1 Kinase
… a conserved RFXV binding site from the PASK/FRAY homology 2 (PF2) domain present in OSR/SPAK. Titration data shows that incubation with a 5-mer and a 20-mer peptide derived from the WNK1 kinase domain displays extensive chemical shift perturbation as assessed by 1H,15N-HSQC. Expression of this …
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An exploration of some aspects of molecular replacement in macromolecular crystallography
This thesis reports work in three areas of X-ray crystallography. An initial chapter describes the structure of a protein, the methods based on the use of X-rays and computer analysis of diffraction patterns to determine crystal structure, and the subsequent derivation of the structure of part or …
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Diffraction spectroscopy of metalloproteins
X-ray absorption is not only element specific, but atom specific: two atoms of the same element in different states or in different neighbourhoods will have slightly different absorption characteristics. These energy dependent atomic form factors are carried over to the diffraction intensities. The …
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Chemical crystallography at the interface of physics, chemistry, and in engineering: structure determination of highly correlated extended solids, main group compounds, coordination complexes, and bioceramics
… and medicine. For these three areas, crystallography has played and continues to play a huge role by providing researchers with the means to determine the structure of a compound and relate these to its properties. This dissertation is highly interdisciplinary, focusing on structure …
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Structural characterisation of ligand, redox and catalytic states in haem enzymes using in crystallo spectroscopies and serial crystallography.
X-ray crystallography is a powerful tool for the study of biomolecules and has determined for instance the structures of numerous enzymes in order to unveil their conformation, interactions with substrates and ligands, and better understand their function. However catalytic processes carried out …