Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 71 for “"Cryptosporidium"”.
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Defining Molecular Mechanism of Egress in Cryptosporidium
Recent studies have identified Cryptosporidium as a major contributor to childhood disease in endemic areas. Current interventions are not ideal where only few have demonstrated anti-cryptosporidial activity and are often associated with relapses in infection. A vaccine to protect or reduce …
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Cryptosporidium and Giardia in calves in Belgium
… and in beef calves 45% (95% CI: 30-64%). The Cryptosporidium prevalence was estimated to be 37% (95% CI: 7-70%) in dairy and 12% (95% CI: 1-30%) in beef calves. Furthermore, 48% of the dairy and 64% of the beef farms had at least one Giardia positive calf, and 32% of the dairy and 24% of the …
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Cryptosporidium Parvum Microbial Adhesion: Interactions Between Sporozoites and Host Cells
Cryptosporidium parvum is a significant protozoal pathogen of both humans and animals worldwide. Since little is known about the mechanisms of attachment and invasion of C. parvum sporozoites to host cells, our goal was to elucidate the mechanism of sporozoite recognition of receptors on the host …
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Evaluation of hops essential oil cytotoxicity and anti-cryptosporidium activity
… predominantly present in HEO, to reduce Cryptosporidium parvum infection in vitro and the potential for their microencapsulation for human or animal applications. Methods. HEO and myrcene in vitro cytotoxicity (IC50) were determined in an HCT-8 intestinal cell model using flow cytometry …
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Novel Nucleic Acid Sensors for the Rapid Detection of Cryptosporidium Parvum
… first customized them for detecting particularly Cryptosporidium parvum, a pathogen whose detection is important, yet presents many challenges. Chapter 2 of this thesis presents a novel test-strip for the detection of C. parvum. The test-strip is designed to detect nucleic acids rather than …
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Molecular Detection for the Apicomplexan Parasites Cyclospora cayetanensis and Cryptosporidium spp.
Background: Cyclospora cayetanensis and Cryptosporidium spp. are intestinal Apicomplexan parasites that can cause severe diarrheal disease in children and immunocompromised hosts. Diagnostic challenges using routine diagnostic methods lead to an underreporting of these parasites, particularly in …
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Fatty Acid-Mediated Inhibition of Host Cell Invasion by Cryptosporidium Parvum
… digests an unsaturated fatty acid that inhibits Cryptosporidium parvum sporozoite invasion of host cells in vitro. A panel of similar lipids with varying chain lengths and degrees of saturation were tested for evidence of inhibitory activity in order to determine the range of specificity. We …
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Understanding the molecular mechanisms controlling gametogenesis and virulence in Cryptosporidium parvum
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2025-03-28 without embargo terms
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Lifecycle Progression And The Sexual Development Of The Apicomplexan Parasite Cryptosporidium Parvum
Cryptosporidium has emerged as one of the leading causes of diarrhea induced-mortality in children and immunocompromised HIV+ individuals. Other than the acute infection, chronic and asymptomatic cryptosporidiosis results in stunted physical and mental development in children. Drugs and vaccines …
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Integrated Optimization of Cryptosporidium Inactivation and Bromate Formation Control in Ozone Contactors
The primary objective of this research was to develop process operation and design recommendations for the simultaneous control of C. parvum oocysts and bromate during ozone disinfection. Elucidation of factors affecting the level of C. parvum inactivation and bromate formation, such as source …
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Roles of surface interaction on Cryptosporidium parvum oocyst transport in subsurface environment
The influence of Cryptosporidium (C.) parvum oocyst and collector surface properties on transport of C. parvum oocysts and microspheres was studied with a radial stagnation point flow (RSPF) cell and 2-dimensional (2-D) micromodels. The quartz or natural organic matter coated quartz surfaces were …
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Modeling fate and transport of Cryptosporidium parvum and rotavirus in overland flow
… of microbial pathogens in drinking water. Cryptosporidium parvum (C. parvum) has been recognized as one of the most frequently occurring microbial contaminants that can cause infection and diarrhea in many mammalian hosts, including humans. About 403,000 of an estimated 1.61 million …
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Effect of Metabolic Enzymes on Amylopectin Content and Infectivity of Cryptosporidium parvum
… stores and subsequently infectivity of Cryptosporidium parvum oocysts/sporozoites in both fresh oocysts and stored oocysts. In addition, glycolytic enzymes and substrates: glucose, glucose-1-phosphate, and glycogen synthase were investigated to determine if they can be used to increase …
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Study of the Cryptosporidium parvum DHFR-TS in the model system Saccharomyces cerevisiae
Cryptosporidium parvum is a ubiquitous protozoan that causes severe gastrointestinal disease. The severe diarrhea that results can be life-threatening, particularly for the very young, old, and immune-compromised. Currently there is no approved therapy for cryptosporidiosis. We have developed a …
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Feline Parasitism: Parasite Prevalence and Evaluation of New Immunoassays for Giardia and Cryptosporidium
… than others. Diagnosing Giardia duodenalis and Cryptosporidium spp. can be difficult because cysts and oocysts shed in the feces are small, shed intermittently, and require a trained technician to consistently identify them. As a result, infections with these protozoan parasites can be missed. …
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Uncovering the role of a Cryptosporidium parvum thrombospondin protein (CpTSP8) in host cell attachment
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-12-01
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Molecular and genetic analysis of Cryptosporidium spp. oocysts : sources and genotypes in the environment
Cryptosporidium parvum is responsible for an acute gastrointestinal disease that is self-limiting in immunocompetent people but potentially life-threatening for the immunocompromised. Until recently, C. parvum was the only species of Cryptosporidium known to cause disease in people, however, …
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