Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"Cryptosporidiosis"”.
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Epidemiology of cryptosporidiosis in dogs in Lusaka District, Zambia
… zoonotic protozoan parasite that causes cryptosporidiosis, a diarrhoeal disease of humans and domestic animals. The parasite has been reported in a variety of domestic animals including dogs. Several species of Cryptosporidium infecting animals have also been reported in humans …
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Epidemiology of cryptosporidiosis in dogs in Lusaka District, Zambia
… zoonotic protozoan parasite that causes cryptosporidiosis, a diarrhoeal disease of humans and domestic animals. The parasite has been reported in a variety of domestic animals including dogs. Several species of Cryptosporidium infecting animals have also been reported in humans …
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Cryptosporidiosis in the Immunosuppressed Mouse and in Cell Culture
<p>Cryptosporidiosis is a parasitic infection primarily of animals that has been recently recognized as an important disease in immunocompromised humans. Most cases to date have occurred in patients with acquired immunodeficiency syndrome (AIDS). Persons with abnormal humoral or cellular immune …
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Novel Design Strategy for Potent and Selective CDPK1 Inhibitors for Cryptosporidiosis
… The unmet clinical need for the treatment of cryptosporidiosis due to the shortage of effective therapeutics has provoked the pursuit of several anti-cryptosporidium approaches. Among those, small molecules targeting the ATP-binding site of CDPK1 have held promise; however, none of the …
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Characterization of Shiga-toxin Producing Escherichia coli Infections and Cryptosporidiosis in South Dakota with Respect to Animal Exposures, 2012
… Patients reported with either STEC or cryptosporidiosis in South Dakota in 2012 were interviewed regarding 7 categories of animal exposure: 1) Petting zoo/fair attendance, 2) animal event/rodeo attendance, 3) feed/pet store visits, 4) farm visits, 5) employment or residence at a farm, …
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Lifecycle Progression And The Sexual Development Of The Apicomplexan Parasite Cryptosporidium Parvum
… the acute infection, chronic and asymptomatic cryptosporidiosis results in stunted physical and mental development in children. Drugs and vaccines are needed to combat cryptosporidiosis, and a better understanding of the biology of the parasite will help in developing therapeutics against the …
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Fatty Acid-Mediated Inhibition of Host Cell Invasion by Cryptosporidium Parvum
… unsaturated free fatty acids in the treatment of cryptosporidiosis.
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Defining Molecular Mechanism of Egress in Cryptosporidium
… egress, while CDPK5 did not seem to play a role. Cryptosporidiosis affects millions of people worldwide with no licensed vaccine available. Results from this study could contribute to the development of an attenuated vaccine for Cryptosporidium. Development of a vaccine that could prevent …
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Molecular and genetic analysis of Cryptosporidium spp. oocysts : sources and genotypes in the environment
… water has been well-documented, and outbreaks of cryptosporidiosis have occurred around the world. The exogenous stage of the organism, the oocyst, is difficult to remove from drinking water supplies because it is resistant to chlorine disinfection and inefficiently filtered. Therefore, a better …
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Study of the Cryptosporidium parvum DHFR-TS in the model system Saccharomyces cerevisiae
… Currently there is no approved therapy for cryptosporidiosis. We have developed a method using the model organism Saccharomyces cerevisiae to rapidly screen for compounds effective against the C. parvum dihydrofolate reductase (DHFR) enzyme. The DHFR enzyme is essential and an effective drug …
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Development of a rapid and sensitive method to detect the parasite Cryptosporidium in drinking water
… for the waterborne intestinal disease called cryptosporidiosis.<br/><br/>Common techniques to detect Cryptosporidium in water include the utilization of filters to trap the oocysts and the examination of the filtered water, observing slides under the microscope. The whole process is time …
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Cryptosporidium Parvum Microbial Adhesion: Interactions Between Sporozoites and Host Cells
… may allow for novel therapeutic strategies for cryptosporidiosis. An in vitro cell suspension binding assay was developed and used to investigate binding between C. parvum sporozoites and host cells. Morphologic features of binding events visualized with this assay were identical to those …
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Cryptosporidium and Giardia in calves in Belgium
Cryptosporidiosis mainly occurs in calves younger than 1 month, and causes a mild to profuse diarrhea. In contrast, a Giardia infection is most frequently diagnosed in calves older than 1 month and clinical symptoms comprise a chronical and intermittent diarrhea, and ill thriving. Cattle are …
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The Novel Long Non-Coding RNA Nostrill Regulates Intestinal Epithelial Defense Against Cryptosporidium parvum and Modulates Microglial-Mediated Neurotoxicity
… novel therapeutic target to enhance treatment of cryptosporidiosis. LncRNAs may help direct proinflammatory responses of microglia, the resident immunocompetent and phagocytic cells in the central nervous system (CNS). Pro-inflammatory microglia are neurotoxic and contribute to the pathogenesis of …
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The Effects of E-Beam Irradiation, Microwave Energy and High Hydrostatic Pressure on Presence and Health Significance of Cryptosporidium parvum in Eastern Oysters (Crassostrea virginica)
… applications to reduce public health risks from cryptosporidiosis in Eastern oysters.
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Evaluation of chemical treatments and ozone on the viability of Cryptosporidium parvum oocysts in fruit juices
… and deer that graze in and around orchards. Cryptosporidiosis can result in a severe illness for previously healthy individuals and a life-threatening illness in immunocompromised individuals. Disease occurs after the ingestion of small infective oocysts (4 to 5 mm in size). The relatively …
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Prevalence and factors associated with cryptosporidium infection among adult HIV positive population in contact with livestock in Namwala District, Zambia
Cryptosporidiosis is a diarrhoeal disease caused by the parasite, Cryptosporidium that can live in the intestine of humans and animals and is passed in the stool of an infected person or animal. In immune compromised individuals, Cryptosporidium infection can be serious, long-lasting and sometimes …
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Evaluation of hops essential oil cytotoxicity and anti-cryptosporidium activity
… explore the effect of encapsulated HEO against cryptosporidiosis in vivo.
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Bad Water, Dirty Politics: Contrasting Governmental Responses to Two U.S. Water Crises
Two of the United States's most destructive water crises, separated by nearly twenty years, occurred in Milwaukee, Wisconsin in 1993 and Flint, Michigan in 2014. This thesis compares and contrasts the two crises, focusing specifically on the differences in local governmental response to each …