Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Cryptococcosis"”.
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Macrophage – cryptococcus interactions during cryptococcosis
The human fungal pathogens Cryptococcus neoformans and C. gattii cause life-threatening infections of the central nervous system. One of the major characteristics of cryptococcal disease is the ability of the pathogen to parasitise upon phagocytic effector cells. Cryptococcus can survive and …
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Analysis of clnical features of cryptococcosis and antifungal susceptibility of clinical isolates in Korea
… susceptibility. We analyzed clinical features of cryptococcosis and antifungal susceptiblity of clinical isolates. METHODS: We analyzed retrospetively 43 cases of cryptococcosis diagnosed in Ajou University hospital from 1995 to 2011. For antifungal susceptibility data, 78 clinical isolates of …
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Cryptococcus neoformans e Cryptococcus gattii: quimiotipagem e correlação com criptococose em hospitais públicos de João Pessoa - PB.
Cryptococcosis is a mycosis in nature systemic and cosmopolitan, caused by infection with Cryptococcus neoformans (opportunistic) and C . gattii (primary pathogen), whose CNS involvement occurs in a slick. The objecti ve was to verify the diagnosis of infection, species identification, clinical …
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The emergence of cryptococcus gattii in British Columbia : veterinary aspects
… or unreported when compared to humans. Animal cryptococcosis cases were identified on Vancouver Island prior to 1999 suggesting the organism may have emerged in the region prior to its identification as a causative agent for human disease; therefore animals may serve as a good sentinel for …
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The Effects of Host-like Environmental Signals and Gene Expression on Capsule Growth in Cryptococcus neoformans
… neoformans</em> is a fungal pathogen that causes cryptococcosis, a disease that kills almost 200,000 people worldwide each year. A unique feature of this deadly yeast is its polysaccharide capsule, which is known to be associated with its virulence. Here, we systematically explore the effects of …
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Disconnecting a Role for DNA Repair in the Pathogenicity of the Human pathogen Cryptococcus neoformans
… every year around 625,000 deaths occur due to Cryptococcosis. A basic understanding of Cryptococcus virulence mechanisms and survival strategies is required to combat the infections and develop therapies through translational research. Considering the evidence of a role of DNA repair in …
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Comparative structural analysis of cytochrome P450 family CYP51 in the genus Cryptococcus
… of the azole drug fluconazole for treating cryptococcosis, a life-threatening fungal infection in immune-compromised patients in poor countries. Studies indicate that mutations in CYP51 confer fluconazole resistance on cryptococcal species. Despite the importance of CYP51 in these species, …
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Intracellular parasitism of macrophages by Cryptococcus
… linked to virulence in a murine model of cryptococcosis, suggesting that this ability might be the cause of the outbreak. Finally, application of high-density whole genome tiled arrays, confocal microscopy and mating assays reveal regulation of mitochondrial activity to be a major driver …
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MONITORAGGIO SIEROLOGICO PER LA SORVEGLIANZA DI PAZIENTI SOTTOPOSTI A TRAPIANTO RENALE IN RELAZIONE AL RISCHIO DI INFEZIONE FUNGINA INVASIVA
Fra tutti gli interventi di trapianto di organo solido, il trapianto di rene, rappresenta quello con la pi ̈ ́ bassa incidenza di infezioni fungine; di tutte le infezioni che si sviluppano in seguito ad un intervento di trapianto di rene, quelle a carico dei funghi risultano essere soltanto il 5%. …
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Sex in Cryptococcus: Signaling, Mating-type Locus Evolution and Gene Silencing
… pathogen that causes cryptococcal meningitis and cryptococcosis, sex has been associated with virulence. To further understand how sex is genetically regulated in C. neoformans, we focused our studies on the evolution of the MAT locus and molecular dissection of the pheromone signaling pathway …
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Niveles de anticuerpos totales y específicos contra proteínas de Cryptococcus neoformans y Cryptococcus gattii en sueros de adultos y niños colombianos con y sin diagnóstico de Criptococosis
Introducción: Cryptococcus neoformans y Cryptococcus gattii causan criptococosis, una micosis potencialmente mortal que mundialmente afecta principalmente a adultos inmunocomprometidos. Objetivo: Contrastar anticuerpos totales y específicos contra antígenos proteicos de C. neoformans y C. gattii en …