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Showing 1 to 2 of 2 for “"Cryoradiolysis"”.
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Spectroscopic characterization of iron-oxygen intermediates in human aromatase (CYP19A1)
… resonance (EPR) spectroscopy and also, cryoradiolysis and cryospectroscopy. The approach I have applied in this project has been that of characterizing the individual fate of reaction intermediates on their way from substrates to products thereby catching them ‘in action’. My …
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Capture and Characterization of Dioxygen Reactive Intermediates in CYP51 Catalysis
The cytochromes P450 (CYPs) are a superfamily of biological catalysts that are ubiquitous throughout the biological domain. CYPs are heme-b containing monooxygenases which oxidize substrates with the help of accessory redox partners. CYP substrates include endogenous compounds required for many …