Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Cryodamage"”.
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Freezing-induced deformation of biomaterials in cryomedicine
… and cryotherapy. Lack of proper understanding of cryodamage that occurs during these applications remains to be the primary bottleneck for development of successful tissue cryopreservation and cryosurgery procedures. An engineering approach based on a view of biological systems as functional …
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Characterization of Maternal Factor MOF/H4K16ac and the Impact of the Cryostress on Bovine Embryonic Development
… embryogenesis. In Chapter III, we assessed the cryodamage in bovine blastocysts during the vitrification-thaw process comparing standard and Ultra-fast cooling rates, at both the transcriptome and epigenome levels. Transcriptome analysis revealed that DNA damage repair pathway genes were …
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Novel Cryoprotective agents to improve the quality of cryopreserved mammalian cells
… and biological pathways associated with cryodamage and the modulatory effects of adding novel CPAs. The proteome profile and the corresponding biological functions were evaluated and iii showed that Nig and Sal protected cells against cryodamage. The additive compounds (Nig and Sal) …
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Analysis of Human Sperm Chromatin Integrity
… fertilization. Spermatozoa rendered immotile by cryodamage were directly microinjected into the perivitelline space of hamster oocytes in order to obtain fertilization and possible chromosomal development.</p> <p>The swim-up-selected spermatozoa showed a higher resistance to the chromatin …
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CatSper: Characterisation in Human Spermatozoa and Clinical Significance
… of donors who were particularly susceptible to cryodamage, which may be of significant clinical relevance, due to the common use of cryopreservation of semen in ART. The present study also describes the novel use of single cell calcium imaging as a sensitive screening tool for calcium defects in …