Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Crossover events"”.
-
Investigating the effects of genetic variation on heterochromatic crossover events in Arabidopsis thaliana
Crossover events result in the reciprocal exchange of genetic material between homologous chromosomes during meiosis. Numerous genetic and environmental factors have been shown to influence the meiotic recombination landscape in many different species. My thesis uses the model plant *Arabidopsis …
-
Diverse outcomes of homologous recombination in the human Y chromosome
… are also the targets of crossing over. Crossover events in palindromes can lead to isochromosome formation and diverse reproductive disorders including sex reversal, male infertility, and Turner syndrome. Second, I demonstrate that a region of the MSY - thought to be recombinationally …
-
Selection for Run1-Ren1 Dihybrid Grapevines Using Microsatellite Markers
… region, corroborating earlier observations that crossover events between homologous chromosomes are suppressed around the Run1 locus.Taken together, the results of this work show that microsatellite marker-assisted selection is a reliable and cost-effective method to combine multiple alleles that …
-
Effect of Werner and Bloom Helicase Deficiencies On Dna Double-Strand Break Repair
… double strand breaks (DSBs) are very deleterious events that occur in cells. Causes can include endogenous agents such as reactive oxygen and nitrogen species, exogenous agents such as ionizing radiation and ultraviolet light, or other sources such as processing of spontaneous DNA lesions or …
-
Understanding Meiotic Recombination and Genomic Organisation of Plant Species
… variation in sexually reproducing species. Crossover events are not distributed randomly along chromosomes and some regions of the genome, like the centromeres, rarely undergo recombination. Modifying crossover levels and distributions via genetic engineering may provide effective tools for …
-
The role of Arabidopsis thaliana heterochromatin component H2A.W in meiotic recombination
… exchange genetic information, also called crossovers. Crossovers break the linkage between genes and create new combinations of alleles which are inherited in the offspring population. Meiotic crossover events can be beneficial to plant breeding programmes, because they facilitate the …
-
Engineering Zymomonas mobilis for the production of biofuels and other value-added products
… this system increases the frequency of double crossover events for the purpose of constructing gene knockouts in the strain. We have also constructed an expression system for the type II CRISPR/CRISPR-associated (Cas) bacterial adaptive immunity system in Z. mobilis. We have shown that the Cas9 …
-
Development of Improved Genetic Methods for Enterococcus Faecium
… into E. faecium, and screening for double-crossover events that can collectively take up to multiple weeks to perform. Additional genetic infrastructure, including robust inducible promoters and sitespecific integration vectors have yet to be developed in E. faecium. Furthermore, a …