Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 84 for “"Crohn's disease"”.
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Microbial Manipulation as a Therapy in Crohn's Disease
Crohn’s disease is a chronic relapsing inflammatory disease of the gastrointestinal tract. Its global incidence and prevalence rates have risen over the last two generations; its burden reflects this rising. Physical, social and psychological morbidity result in reduced quality of life and …
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Consequences of Aryl Hydrocarbon Receptor Activation in Crohn's Disease
… such as indole-3-carbinol (I3C) and indirubin. Crohn's disease, a chronic inflammatory state of the gastrointestinal tract, affects millions worldwide; however, the exact cause is unknown and treatments do not cure the disease. The role of the AhR in mucosal immune responses is not well …
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Consequences of Aryl Hydrocarbon Receptor Activation in Crohn's Disease
… such as indole-3-carbinol (I3C) and indirubin. Crohn's disease, a chronic inflammatory state of the gastrointestinal tract, affects millions worldwide; however, the exact cause is unknown and treatments do not cure the disease. The role of the AhR in mucosal immune responses is not well …
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Evaluation of Select Food Additive Exposures in Children with Crohn's Disease
… Select Food Additive Exposures in Children with Crohn’s Disease C Kaiulani Swan Chair of the Supervisory Committee: Johanna Lampe, University of Washington Research Professor Epidemiology Crohn’s Disease (CD) is a chronic, debilitating inflammatory bowel disease and recent research has revealed …
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Crohn's disease : enteral nutrition practices of registered dietitians in New Mexico
… (RDs) in New Mexico for patients with active Crohn’s Disease (CD) and to compare these recommended formulations to the ASPEN and ESPEN guidelines. Methods: The link to an electronic survey was e-mailed to 109 potentially eligible RDs employed at acute care facilities in New Mexico during the …
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Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
… therefore remains that, at the present time, Crohn's disease is still an enigma. The aetiology and pathogenesis are obscure, the clinical findings and progression of the disease are unpredictable and the histological findings are often nonspecific. With this in mind, this dissertation attempts …
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Intestinal permeability to polyethylene glycol 400 in patients with Crohn's disease
… factor in the pathogenesis of inflammatory bowel disease. The relevant literature was reviewed. Intestinal permeability to Polyethylene glycol 400 in patients with Crohn' s disease, their relatives and healthy controls was examined and the data compared with studies of small bowel permeability to …
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Predicting poor outcome Crohn's disease at the time of first diagnosis
Over time, the majority of patients with Crohn's disease (CD) will develop irreversible gastrointestinal (GIT) damage, notably strictures or fistulas, impacting negatively on quality of life and resulting in hospitilisation and surgery. Early and aggressive drug therapy with immunomodulators (IMMs) …
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Crohn's Disease and the Young Adult Couple: An Interpretative Phenomenological Study
There are over 700,000 individuals living with Crohn's disease in the United States. Crohn's disease is a chronic inflammatory bowel illness that can have debilitating effects on individuals and their partners. There is ample literature on the various medical effects of Crohn's disease on the …
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Metabolomic analysis of the interleukin-10-deficient mouse model of Crohn's disease
Crohn’s disease is an inflammatory disorder of the bowel, arising from the dysregulation of intestinal mucosal immunity. The interleukin-10-deficient (IL10-/-) mouse develops intestinal inflammation with similar characteristics to Crohn’s disease, due to the loss of immune tolerance towards …
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Evaluation of Intestinal Microbial Diversity and a New Antibiotic Regimen in Crohn's Disease Patients
<p>Crohn's disease (CD) is a chronic granulomatous inflammatory bowel disease involving Mycobacterium avium subspecies paratuberculosis (MAP). Other microorganisms such as adherent-invasive Escherichia coli (AIEC) have also been proposed in CD association. To date, only one study investigated both …
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The role of genetic alterations in the gut-joint axis of Crohn's disease and Spondyloarthropathies
… intestine and joint. Further research in both disease entities is mandatory to investigate how bacterial components are transported to extraintestinal organs. Functional study of isolated monocytes of CD patients demonstrated for the first time a disturbed immunological response in single …
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Molecular Typing Of Mycobacterial Isolates Cultured From The Tissue Of Inflammatory Bowel Disease (Crohn's Disease) Patients
… etiology and pathogenesis of inflammatory bowel disease (IBD) including Crohn's Disease (CD), has been investigated. The fastidious characteristics and cross reactivity of MAP with other members in Mycobacteria have produced significant challenges in their detection and identification. In this …
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Evaluating the role of Kinesiology, as an adjunct therapy, in the management of patients with Crohn's disease
… would improve the management of patients with Crohn's disease. One hundred and fifty consecutive Crohn's disease patients, attending the Gastrointestinal Clinic at Groote Schuur Hospital, were randomly assigned to a Kinesiology (n=50) and a Control Group (n=50). In order to assess the effect of …
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Discovering the mechanism of action of nutritional therapy and evolving an innovative formula for the treatment of Crohn's disease
… gut inflammation and induce remission in active Crohn disease (CD). However, PF’s used for EEN therapy were developed for nutritional support and not for therapeutic roles. The aim of this thesis was to identify and describe components of PF that actively suppress inflammation and to investigate …
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Audit of the reporting adequacy of magnetic resonance enterograph performed in patients with Crohn's disease at Groote Schuur Hospital
… CD is an idiopathic inflammatory bowel disease with a predilection for the terminal ileum and the colon. MRE is the cornerstone imaging modality for evaluating and monitoring CD. This audit aims to assess the adequacy of radiology reports for MRE in CD patients, performed at GSH. …
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