Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 91 for “"Crohn's"”.
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Microbial Manipulation as a Therapy in Crohn's Disease
Crohn’s disease is a chronic relapsing inflammatory disease of the gastrointestinal tract. Its global incidence and prevalence rates have risen over the last two generations; its burden reflects this rising. Physical, social and psychological morbidity result in reduced quality of life and …
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Consequences of Aryl Hydrocarbon Receptor Activation in Crohn's Disease
… such as indole-3-carbinol (I3C) and indirubin. Crohn's disease, a chronic inflammatory state of the gastrointestinal tract, affects millions worldwide; however, the exact cause is unknown and treatments do not cure the disease. The role of the AhR in mucosal immune responses is not well …
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Consequences of Aryl Hydrocarbon Receptor Activation in Crohn's Disease
… such as indole-3-carbinol (I3C) and indirubin. Crohn's disease, a chronic inflammatory state of the gastrointestinal tract, affects millions worldwide; however, the exact cause is unknown and treatments do not cure the disease. The role of the AhR in mucosal immune responses is not well …
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Cellular Immune Response And Gene Expression Profiling In Crohn's Dise
Despite the chronic debate in the etiology of crohn's disease (cd), a debilitating inflammatory bowel disease (ibd) closely related to ulcerative colitis (uc), an emerging interest in a possible mycobacterial role has been marked. Granuloma and pathologic manifestations in cd resemble aspects found …
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Evaluation of Select Food Additive Exposures in Children with Crohn's Disease
… Select Food Additive Exposures in Children with Crohn’s Disease C Kaiulani Swan Chair of the Supervisory Committee: Johanna Lampe, University of Washington Research Professor Epidemiology Crohn’s Disease (CD) is a chronic, debilitating inflammatory bowel disease and recent research has revealed …
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Crohn's disease : enteral nutrition practices of registered dietitians in New Mexico
… (RDs) in New Mexico for patients with active Crohn’s Disease (CD) and to compare these recommended formulations to the ASPEN and ESPEN guidelines. Methods: The link to an electronic survey was e-mailed to 109 potentially eligible RDs employed at acute care facilities in New Mexico during the …
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Crohn's Disease : diagnostic and prognostic indicators with special reference to granulomas
… therefore remains that, at the present time, Crohn's disease is still an enigma. The aetiology and pathogenesis are obscure, the clinical findings and progression of the disease are unpredictable and the histological findings are often nonspecific. With this in mind, this dissertation attempts …
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Intestinal permeability to polyethylene glycol 400 in patients with Crohn's disease
… to Polyethylene glycol 400 in patients with Crohn' s disease, their relatives and healthy controls was examined and the data compared with studies of small bowel permeability to other similar sized probes. A new technique of analysis of urinary Polythylene Glycol 400 by High Performance …
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Predicting poor outcome Crohn's disease at the time of first diagnosis
Over time, the majority of patients with Crohn's disease (CD) will develop irreversible gastrointestinal (GIT) damage, notably strictures or fistulas, impacting negatively on quality of life and resulting in hospitilisation and surgery. Early and aggressive drug therapy with immunomodulators (IMMs) …
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Crohn's Disease and the Young Adult Couple: An Interpretative Phenomenological Study
There are over 700,000 individuals living with Crohn's disease in the United States. Crohn's disease is a chronic inflammatory bowel illness that can have debilitating effects on individuals and their partners. There is ample literature on the various medical effects of Crohn's disease on the …
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Metabolomic analysis of the interleukin-10-deficient mouse model of Crohn's disease
Crohn’s disease is an inflammatory disorder of the bowel, arising from the dysregulation of intestinal mucosal immunity. The interleukin-10-deficient (IL10-/-) mouse develops intestinal inflammation with similar characteristics to Crohn’s disease, due to the loss of immune tolerance towards …
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Evaluation of Intestinal Microbial Diversity and a New Antibiotic Regimen in Crohn's Disease Patients
<p>Crohn's disease (CD) is a chronic granulomatous inflammatory bowel disease involving Mycobacterium avium subspecies paratuberculosis (MAP). Other microorganisms such as adherent-invasive Escherichia coli (AIEC) have also been proposed in CD association. To date, only one study investigated both …
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The role of genetic alterations in the gut-joint axis of Crohn's disease and Spondyloarthropathies
Next to the known clinical and immunological links between CD and SpA, we demonstrate in this work a genetic connection between these two disorders. Carriership of CD-related CARD15 polymorphisms in SpA patients is associated with the presence of chonic gut inflammation, similar to CD. Whether …
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Molecular Typing Of Mycobacterial Isolates Cultured From The Tissue Of Inflammatory Bowel Disease (Crohn's Disease) Patients
… of inflammatory bowel disease (IBD) including Crohn's Disease (CD), has been investigated. The fastidious characteristics and cross reactivity of MAP with other members in Mycobacteria have produced significant challenges in their detection and identification. In this two year pilot study, an …
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Evaluating the role of Kinesiology, as an adjunct therapy, in the management of patients with Crohn's disease
… would improve the management of patients with Crohn's disease. One hundred and fifty consecutive Crohn's disease patients, attending the Gastrointestinal Clinic at Groote Schuur Hospital, were randomly assigned to a Kinesiology (n=50) and a Control Group (n=50). In order to assess the effect of …
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Discovering the mechanism of action of nutritional therapy and evolving an innovative formula for the treatment of Crohn's disease
… gut inflammation and induce remission in active Crohn disease (CD). However, PF’s used for EEN therapy were developed for nutritional support and not for therapeutic roles. The aim of this thesis was to identify and describe components of PF that actively suppress inflammation and to investigate …
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