Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Crohn's disease"”.
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Evolution of Surgery Risk in Crohn's Disease
While many individuals with Crohn’s disease require surgery for management, the risks of surgery are not well characterized in population-based studies. Advances in medical management may have influenced the risk of surgery over time. However, studies have not adequately evaluated the effect of …
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Towards a translational understanding of colonic bacteria in Crohn's disease pathology
Crohn’s disease (CD) is a chronic inflammatory condition of unknown aetiology, with the microbiota thought to be a major contributor to the disease. This thesis aimed to investigate the potential role of the gut microbiota in this context. The approaches taken were to examine CD associated …
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A Geographical Exploration of Inflammatory Bowel Disease
A chronic disease that afflicts 200 000 Canadians of all ages, inflammatory bowel disease has no known cure or aetiology. Using socioeconomic Census variables, population-level models of inflammatory bowel diseases – Crohn's disease and ulcerative colitis – were made for two large cities in Alberta …
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Symptom burden in individuals with inflammatory bowel disease: a mixed methods study
… of individuals with inflammatory bowel disease (IBD). An explanatory sequential mixed methods study was conducted. A cross-sectional, correlational survey was first undertaken. Symptom burden was measured using a modified disease specific version of the Memorial Symptom Assessment Scale, …
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Investigating the host-microbe dialogue in aging
… in the context of aging and life stage related diseases. The focus was maintained on key inter-kingdom signalling molecules, host produced but bacterially modified Bile acids (BAs) and on dietary microbially derived Fatty acids (FAs) as key elements to indicate gut microbial potential impactful …
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Towards a cognitive neurobiology of brain-gut axis disorders
… bowel syndrome (IBS) and inflammatory bowel disease (IBD). Despite a growing understanding of the neurobiology of brain-gut axis dysfunction, there is a relative paucity of investigations into how the various factors involved in dysregulating the brain-gut axis, including stress, immune …