Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Critical Limb Ischemia"”.
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Co-Delivery of Peptide QK and WKYMVm for Minimally Invasive Therapeutic Angiogenesis in Treating Critical Limb Ischemia
Critical Limb Ischemia (CLI) is a leading cause of mortality among vascular diseases. Current surgical treatments often fail due to the ineffective restoration of blood flow in the diseased vasculature, leading to high rates of amputation and mortality. The delivery of therapeutic peptides emerges …
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Pattern and distribution of peripheral arterial disease in diabetic patients with critical limb ischemia (Rutherford Clinical Category 4-6)
… foot arch status in diabetic patients with critical limb ischaemia Methods: This is a one year prospective study -(January 2014 to December 2014) carried out on consecutive patients seen at Groote Schuur Hospital, Vascular Department. The inclusion criteria is: diabetic patients ≥18 years of …
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Femoro-distal bypass surgery at Groote Schuur Hospital: a 4-year retrospective study
The term "critical limb ischemia", while only defined in recent years by international consensus and objective arterial pressure measurements, has been recognized by surgeons since the dawn of reconstructive vascular surgery fifty years ago. Patients present with increasingly severe and intolerable …
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Arterial Thrombosis in Factor V Leiden or Activated Protein C Resistance. Clinical and Experimental Studies.
… amputation rate and inflammatory mediators in critical limb ischemia (CLI) patients with Factor V Leiden did not find any significant difference in inflammatory mediators between critical limb ischemia patients with Factor V Leiden and non-carriers. There was neither a significant difference in …
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Cukriniu diabetu sergančių ligonių blauzdos arterijų kraujotaką atkuriančių metodų įvertinimas /
… the early postoperative period for patients with critical limb ischemia. Diabetes does have a tendency to worsen bypass function and long-term restoration of blood circulation after endovascular procedures. And also that for diabetic patients bypass functioning after two years is better than blood …
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Sex Differences in Collateral Remodeling Following Hindlimb Arterial Occlusion
… occlusive disease and associated likelihood of critical limb ischemia in women, as well as worse prognosis and decreased survival post myocardial infarction. Therefore, understanding the possible differences in underlying vascular compensation mechanisms is crucial. With arterial occlusions, …
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The Soluble Form of the Axl Receptor Tyrosine Kinase
… The third study investigated patients with critical limb ischemia. The patients had high Gas6 and sAxl, and both proteins correlated with several inflammatory markers. Patients with high Gas6 and sAxl had poorer prognosis with higher mortality, independent of age and gender. The fourth study …
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Keratose Hydrogels Promote Vascular Smooth Muscle Differentiation from c-kit+ Human Cardiac Stem Cells: Underlying Mechanism and Therapeutic Potential
… capability, we selected a murine model of critical limb ischemia (CLI). CLI was induced in 3 groups (n=15/group) of adult mixed gender NSG mice by excising the femoral artery and vein, and then treated the mice with either PBS (termed as PBS-treated), Cells differentiated on TCPS (termed as …
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Endothelial Cell-Specific Knockout of Meis1 Protects Ischemic Hindlimb Through Vascular Remodeling
… conditions, such as atherosclerosis or diabetes. Critical limb ischemia (CLI) is a severe form of PAD associated with high morbidity and mortality. Currently, no effective and permanent treatments are available for this disease. The current endovascular medications (e.g., angioplasty or stents) …