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Showing 1 to 3 of 3 for “"CrebH"”.
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Crebh, A Novel Liver Clock Keeper For Energy Metabolism
… binding protein 3-like 3 (CREB3L3, also known as CREBH) is a liver-enriched, endoplasmic reticulum (ER)-tethered transcription factor known to regulate hepatic acute-phase response and energy homeostasis under stress conditions. Here, we demonstrate that CREBH is regulated by the circadian clock …
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Role Of Crebh In Endotoxin Mediated Modulation Of Hepatic Metabolism
… anchored liver-specific transcription factor CREBH (cAMP-responsive element-binding protein, hepatocyte-specific), which is activated by ER stress, inflammatory stimuli, and metabolic signals. Proinflammatory cytokines TNFα, IL6, and IL1β, bacterial endotoxin lipopolysaccharide, insulin …
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The Role Of Crebh In Hepatic Energy Regulation Under Metabolic Stress
… cyclic AMP responsive element-binding protein (CREBH) is a transcription factor that is preferentially expressed in the liver and localized in the endoplasmic reticulum (ER) membrane. CREBH is known to be activated by ER stress, inflammatory stimuli, and metabolic signals to regulate hepatic …