Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Craniofacial development"”.
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The Role of MicroRNAs in Craniofacial Development
… pharyngeal arch and/or the frontonasal process. Craniofacial clefting can result from genetic and teratogenic disruptions affecting the growth and development of the first pharyngeal arch. Many of the molecular pathways regulating normal and abnormal growth and development of the first arch have …
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MyosinX is Required For Craniofacial Development in Danio Rerio
<p>Craniofacial development is the process of laying early cartilage and bone patterns in the anterior region of the embryo, which ultimately results in shaping the structure of the face and head of an organism. Craniofacial abnormalities in humans, such as cleft lip and palate, are among the most …
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The extreme anterior domain coordinates brain and craniofacial development
… of different cell types and undergo distinct developmental programs. However, development of the brain and various parts of the face may be coordinated so that tissues form in the correct order and scale to each other appropriately. Work presented here demonstrates that the Xenopus Extreme …
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The Neurotrophic Influence on Craniofacial Development Subsequent to in Utero Unilateral Transection of the Trigeminal(V) Nerve
… tissue morphogenesis, subsequent development and growth, and maintenance of the craniofacial complex. This research is believed to be the first time that such a procedure has been attempted on a mammalian fetus. Each animal was clinically evaluated and then sacrificed at specific …
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Gene Discovery In Nonsyndromic Cleft Lip With Or Without Cleft Palate
… to demonstrate the role of these genes in normal craniofacial development. Using genome scan and candidate gene approaches, novel associations with NSCLP were identified. These include MYH9 (7 SNPs, 0.009≤p<0.05), Wnt3A (4 SNPs, 0.001≤p≤0.005), Wnt11 (2 SNPs, 0.001≤p≤0.01) and CRISPLD2 (4 SNPs, …
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Characterization of the TCOF1 Gene Using a Neuroblastoma Cell Line and a Mouse Model
… Collins syndrome (TCS) is an autosomal dominant craniofacial development disorder and is caused by mutations in the TCOF1 gene. The TCOFl protein treacle is a nucleolar protein and may function in ribosome biogenesis.Previously, we identified downstream candidate genes using microarray analysis …
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Impact of Childhood Obesity on Dental Crowding, Arch Shape, and Arch Width
… and has been shown to influence growth and craniofacial development. Obese children have been shown to have precocious dental development. This study explores the effects of obesity on dental crowding, arch shape, and arch width in children from age 5-17.9 with various body mass indices …
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Fzd6, Matn2 and Slc25A32, Possible Candidate Genes In Nonsyndromic Cleft Lip and Palate
… is part of the WNT pathway, which is involved in craniofacial development, including midface development and upper lip fusion. Our novel findings suggest that an alteration in <em>FZD6</em> gene regulation may perturb this tightly controlled biological pathway and in turn contribute to the …
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Tratamento ortodôntico de pacientes com agenesia de incisivos laterais superiores
The "agenesis" term is attributed to non-development of one or more teeth – up to six. Genetics and inheritance are the main etiological factors of dental anomalies, especially agenesis. The most affected elements are the third molars often followed by lower premolars, maxillary lateral incisors …
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Bmp-Signaling Regulates A Common Transcriptional Program to Control Facial Form and Skeletal Morphogenesis
<p>Much of the craniofacial skeleton, such as the skull vault, mandible and midface, develops through direct, intramembranous ossification of the cranial neural crest (CNC) derived progenitor cells. Bmp-signaling plays critical roles in normal craniofacial development, and Bmp4 deficiency results …
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Cellular and Developmental Functions of The Xenopus Arvcf-Catenin:Kazrin Complex
… evidence that xARVCF and xKazrin participate in craniofacial development, with effects observed upon the neural crest. Finally, I found that xKazrinA associates further with delta-catenin and p0071-catenin, but not with p120-catenin, suggesting that Kazrin interacts selectively with additional …
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Genetic Pathway Analysis of Abnormal Facial Development In Nonsyndromic Cleft Lip and Palate
… without cleft palate (NSCLP) is the most common craniofacial birth defect resulting from incomplete fusion of the facial prominences during development, which leaves a gap in the lip, primary palate and/or the secondary palate. NSCLP affects 135,000 NSCLP newborns worldwide each year based on a …
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Molecular Basis and Modification of a Neural Crest Deficit in a Down Syndrome Mouse Model
… replicates many DS phenotypes including craniofacial alterations such as a small, dysmorphic mandible, midface, and maxilla. Other mouse models, such as the Ts1Rhr which contains a triplication of 33 Hsa 21 orthologs, have been used to better understand the genes responsible for …
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Μελέτη της σκελετικής μορφολογίας του ρινογναθιαίου συμπλέγματος σε άτομα με παραμορφώσεις του ρινικού διαφράγματος
THE AIM OF THIS STUDY WAS TO EVALUATE THE ANTERO-POSTERIOR AND VERTICAL DIMENSIONS OF THE NASAMAXILLARY COMPLEX IN PATIENTS PRESENTING NASAL SEPTUM DEFORMITIES. NINETEEN ANGULAR AND LINEAR MEASUREMENTS WERE PERFORMED ON EACH CEPHALOGRAM THE VALUES WERE TABULATED AND STATISTICALLY ANALYSED …