Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"CpG-SNPs"”.
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The Human Pancreatic Islet Methylome and Its Role in Type 2 Diabetes
… non-diabetic donors (Study III). Nearly 1,500 CpG sites (853 genes) were differentially methylated in T2D islets, with the majority showing decreased DNA methylation. 102 genes showed both altered DNA methylation and mRNA expression in T2D islets, including CDKN1A, PDE7B, SEPT9 and EXOC3L2. Our …
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Molecular Epidemiology of Breast Cancer
… methylation potential, in the form of common CpG-SNPs, might affect cancer risk. We conducted a large study in five different independent population cohorts (comprising totally >3000 cases) to test this hypothesis in genes previously implicated either in breast cancer or methylation. In this …