Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"CpG island promoters"”.
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Identification of Factors Involved In Dna Methylation of Cpg-Island-Promoters
… increased DNA methylation levels at promoter CpG islands (CGI). About one-fourth of empirically defined human promoters are surrounded by or contain clustered repetitive elements. It was previously observed that a sharp transition of methylation occurs between highly methylated repetitive …
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Epigenetic silencing of BRCA1 and maspin in sporadic breast cancer
… cytosine methylation of the BRCA1 and maspin CpG island promoters is a common event in the inactivation of these genes in sporadic breast cancer cell lines. Furthermore, we show that the methylation-associated inactivation of BRCA1 occurs in 15-30% of sporadic breast cancer patient specimens …
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The genome-wide analysis of the specification and activation of human chromosomal DNA replication origin sites
… discrete replication origins and showed that CpG islands and CpG island-promoters were dominant features associated with high origin activity. Origins identified by ds-iniSeq (ds-iniSeq origins) strongly colocalised with transcription start sites and active genes, but transcriptional activity …