Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"CpG island methylator phenotype (CIMP)"”.
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Impact of the gut microbiota on DNA methylation in colorectal cancer
The CpG Island Methylator Phenotype (CIMP) is a distinct form of aberrant DNA methylation in cancer, and it is seen in 20-40% of colorectal cancers (CRC) where its causes remain elusive. Intestinal microbiota represents an important environmental component implicated in CRC development. …
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Rna-Sequencing Applications: Gene Expression Quantification and Methylator Phenotype Identification
… the application of RNA-seq data to identify the CpG island methylator phenotype (CIMP) by integrating datasets of mRNA expression level and DNA methylation status.</p> <p>Section 1: The cost of DNA sequencing has reduced dramatically in the past decade. Consequently, genomic research increasingly …