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Showing 1 to 2 of 2 for “"Coxsackievirus Infections"”.
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Assay and Purification of Coxsackievirus B3
The problem. Which of the available methodologies for the purification for Coxsackie virus B3 (CB3), a Picornavirus provide the highest degree of purity with the greatest yield. The procedure. Quantitative methods for the assay and purification of CB3 were developed. CB3 was propagated in buffalo …
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The Tradeoffs for a Viral Mutant with Enhanced Replication Speed
… in cultured cells. By sequentially passaging coxsackievirus B3 in cultured cells and collecting the very earliest progeny, we selected for increased replication speed. We found that a single mutation in a viral capsid protein, VP1-F106L, was sufficient for the fast-replication phenotype. …