Global ETD Search
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Showing 1 to 13 of 13 for “"Coxiella burnetii"”.
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Inhibition of TFEB activation promotes Coxiella burnetii growth
Coxiella burnetii is the etiologic agent of Q fever, a zoonotic disease characterized by flu-like sickness in acute cases; endocarditis may occur and turn deadly if not treated correctly in chronic patients. Coxiella, an obligate intracellular bacterium, requires establishment of a replicative …
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The epidemiology of Coxiella burnetii in goats in Indiana
Coxiella burnetii is an obligate, intracellular bacterium and the etiologic agent of the zoonotic disease Q fever. Through the presence of an environmentally resilient small cell variant, C. burnetii can persist outside of a host in the face of extremes in temperature, humidity, and pressure. C. …
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Evasion Of Innate Immunity By The Pathogen Coxiella Burnetii
… innate immune response to the bacterial pathogen Coxiella burnetii. This intracellular pathogen has an intimate association with host cells and evades multiple host defense pathways, making it a unique model system in which to study pathogen countermeasures. C. burnetii infects alveolar …
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Mobile genetic elements in Coxiella burnetii: Friends, foes or just indifferent?
… genome of the obligate intracellular pathogen Coxiella burnetii contains a large number of mobile genetic elements including two group I introns and an intervening sequence (IVS) that interrupt the 23S rRNA gene; an intein within dnaB (encoding replicative DNA helicase) and a homing …
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Mobile genetic elements in Coxiella burnetii: Friends, foes or just indifferent?
… genome of the obligate intracellular pathogen Coxiella burnetii contains a large number of mobile genetic elements including two group I introns and an intervening sequence (IVS) that interrupt the 23S rRNA gene; an intein within dnaB (encoding replicative DNA helicase) and a homing …
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Recruitment and function of ORP1L on the Coxiella burnetii parasitophorous vacuole
Coxiella burnetii, the zoonotic agent of human Q fever and chronic endocarditis, is an obligate intracellular bacterial pathogen. The Coxiella intracellular niche, a large, lysosome-like parasitophorous vacuole (PV), is essential for bacterial survival and replication. There is growing evidence …
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The Role of Mammalian Lipid Transport Protein ORP1 During Coxiella Burnetii Infection
Coxiella burnetii is an intracellular bacterium that causes the human disease Q fever. C. burnetii is transmitted from infected animals to humans through inhalation of infectious droplets. Acute Q fever is a flu-like illness lasting 10-14 days. Patients often have respiratory symptoms and present …
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The Prevalence of the Q-fever Agent Coxiella burnetii in Ticks Collected from an Animal Shelter in Southeast Georgia
… caused by a worldwide-distributed bacterium Coxiella burnetii. Ticks are vectors of the Q-fever agent but play a secondary role in transmission because the agent is also transmitted via aerosols. Most Q-fever studies have focused on farm animals but not ticks collected from dogs in animal …
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One Health investigation at abattoirs in South Africa
… Cape province; assessing seropositivity of Coxiella burnetii, Toxoplasma gondii and Brucella spp. antibodies in African abattoir workers with meta-analysis; detect antibodies to zoonotic pathogens (C. burnetii, T. gondii and Brucella spp.) and characterize Brucella spp. in livestock …
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Prevalence and environmental risk factors for ten zoonoses in two cree communities of James Bay (Canada
… seroprevalence are: Leptospira sp. (23%), Coxiella burnetii, Francisella tularensis (17%, titer > 1/20), Toxoplasma gondii (5%), the Sin Nombre virus (0%), two of the virus of the California serogroup (10%) (Snowshoe hare and Jamestown Canyon viruses) and of than less 5% for Echinococcus …
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Structure-Based Drug Design Against a Biosecurity Pathogen
Coxiella burnetii, a gram-negative Gammaproteobacterium, causes the human disease Q-fever. It displays a biphasic lifestyle, with a metabolically constrained small cell variant form enabling survival in the environment. Infection through aerosolization triggers conversion to the metabolically …
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Trobicúlidos y trombiculiasis en La Rioja
… spp., Anaplasma phagocytophilum, Borrelia spp., Coxiella burnetii, Bartonella spp. and Orientia tsutsugamushi in chiggers, and 4) Clinical characterization of trombiculiasis in La Rioja. Our data have shown the coincidence between the seasonality of human and canine cases of trombiculiasis and …
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Detection of zoonotic bacterial pathogens in multiple hosts using a microbiome approach and molecular characterization of Anaplasma phagocytophilum
… Bartonella spp., spotted fever group Rickettsia, Coxiella burnetii and Leptospira spp. Low levels of West Nile and Sindbis, but no Rift Valley fever virus exposure were found. In a separate study, the molecular detection of a bacterium closely related to Anaplasma phagocytophilum in dog samples …