Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 19 of 19 for “"Coxiella"”.
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Inhibition of TFEB activation promotes Coxiella burnetii growth
Coxiella burnetii is the etiologic agent of Q fever, a zoonotic disease characterized by flu-like sickness in acute cases; endocarditis may occur and turn deadly if not treated correctly in chronic patients. Coxiella, an obligate intracellular bacterium, requires establishment of a replicative …
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The epidemiology of Coxiella burnetii in goats in Indiana
Coxiella burnetii is an obligate, intracellular bacterium and the etiologic agent of the zoonotic disease Q fever. Through the presence of an environmentally resilient small cell variant, C. burnetii can persist outside of a host in the face of extremes in temperature, humidity, and pressure. C. …
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Evasion Of Innate Immunity By The Pathogen Coxiella Burnetii
… innate immune response to the bacterial pathogen Coxiella burnetii. This intracellular pathogen has an intimate association with host cells and evades multiple host defense pathways, making it a unique model system in which to study pathogen countermeasures. C. burnetii infects alveolar …
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Recruitment and function of ORP1L on the Coxiella burnetii parasitophorous vacuole
Coxiella burnetii, the zoonotic agent of human Q fever and chronic endocarditis, is an obligate intracellular bacterial pathogen. The Coxiella intracellular niche, a large, lysosome-like parasitophorous vacuole (PV), is essential for bacterial survival and replication. There is growing evidence …
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Mobile genetic elements in Coxiella burnetii: Friends, foes or just indifferent?
… genome of the obligate intracellular pathogen Coxiella burnetii contains a large number of mobile genetic elements including two group I introns and an intervening sequence (IVS) that interrupt the 23S rRNA gene; an intein within dnaB (encoding replicative DNA helicase) and a homing …
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Mobile genetic elements in Coxiella burnetii: Friends, foes or just indifferent?
… genome of the obligate intracellular pathogen Coxiella burnetii contains a large number of mobile genetic elements including two group I introns and an intervening sequence (IVS) that interrupt the 23S rRNA gene; an intein within dnaB (encoding replicative DNA helicase) and a homing …
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The Role of Mammalian Lipid Transport Protein ORP1 During Coxiella Burnetii Infection
Coxiella burnetii is an intracellular bacterium that causes the human disease Q fever. C. burnetii is transmitted from infected animals to humans through inhalation of infectious droplets. Acute Q fever is a flu-like illness lasting 10-14 days. Patients often have respiratory symptoms and present …
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The Prevalence of the Q-fever Agent Coxiella burnetii in Ticks Collected from an Animal Shelter in Southeast Georgia
… caused by a worldwide-distributed bacterium Coxiella burnetii. Ticks are vectors of the Q-fever agent but play a secondary role in transmission because the agent is also transmitted via aerosols. Most Q-fever studies have focused on farm animals but not ticks collected from dogs in animal …
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Η ΝΟΣΟΣ ΤΩΝ ΛΕΓΕΩΝΑΡΙΩΝ ΣΤΗΝ ΕΛΛΑΔΑ
… AND PARAINFLUENZA VIRUSES, ADENOVIRUS AND COXIELLA BURNETTI. WE FOUND TWO PATIENTS WITH LEGIONNAIRE'S DISEASE AS SUGGESTED BY POSITIVE AND RISING TITERS OF ANTIBODIES AGAINST L.PNEUMOPHILA. ONE MORE PATIENT HAD POSITIVE BUT NOT INCREASING TITERS, INDICATING PREVIOUS INFECTION . WE ALSO HAD …
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Characterization of the Bacterial Microbiome of Exotic Tick Species Collected from Migratory Birds
… </em>(actinobacteria). Co-occurrence of <em>Coxiella </em>and <em>Francisella </em>were observed in three species: <em>Amblyomma geayi, Amblyomma coelebs, and Amblyomma calacaratum</em>. <em>Coxiella </em>had majority in only <em>Amblyomma geayi</em>. The overall highest diversity at genus …
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Structure-Based Drug Design Against a Biosecurity Pathogen
Coxiella burnetii, a gram-negative Gammaproteobacterium, causes the human disease Q-fever. It displays a biphasic lifestyle, with a metabolically constrained small cell variant form enabling survival in the environment. Infection through aerosolization triggers conversion to the metabolically …
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One Health investigation at abattoirs in South Africa
… Cape province; assessing seropositivity of Coxiella burnetii, Toxoplasma gondii and Brucella spp. antibodies in African abattoir workers with meta-analysis; detect antibodies to zoonotic pathogens (C. burnetii, T. gondii and Brucella spp.) and characterize Brucella spp. in livestock …
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Prevalence and environmental risk factors for ten zoonoses in two cree communities of James Bay (Canada
… seroprevalence are: Leptospira sp. (23%), Coxiella burnetii, Francisella tularensis (17%, titer > 1/20), Toxoplasma gondii (5%), the Sin Nombre virus (0%), two of the virus of the California serogroup (10%) (Snowshoe hare and Jamestown Canyon viruses) and of than less 5% for Echinococcus …
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Formulating and Processing of a Nutritionally Enhanced Extended Shelf-Life Fluid Milk and Egg Mixture
… The process was more than sufficient to destroy Coxiella burnetti and Salmonella senftenberg which were the most heat resistant organisms of concern in processing this milk and egg mix. The spoilage organisms received 2,200 D and 425 D processes, respectively, which were more than adequate for …
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Trobicúlidos y trombiculiasis en La Rioja
… spp., Anaplasma phagocytophilum, Borrelia spp., Coxiella burnetii, Bartonella spp. and Orientia tsutsugamushi in chiggers, and 4) Clinical characterization of trombiculiasis in La Rioja. Our data have shown the coincidence between the seasonality of human and canine cases of trombiculiasis and …
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Detection of zoonotic bacterial pathogens in multiple hosts using a microbiome approach and molecular characterization of Anaplasma phagocytophilum
… Bartonella spp., spotted fever group Rickettsia, Coxiella burnetii and Leptospira spp. Low levels of West Nile and Sindbis, but no Rift Valley fever virus exposure were found. In a separate study, the molecular detection of a bacterium closely related to Anaplasma phagocytophilum in dog samples …
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Cambios en el espectro etiológico de la fiebre de duración intermedia en el sur de Europa
… serológicas seriadas (Brucella melitensis, Coxiella burnetti, Rickettsias typhi y conorii, CMV y VEB), ARN-VIH, hemocultivos con fiebre y extracción de muestras sanguíneas para técnicas microbiológicas adicionales para casos sin diagnóstico o con diagnóstico dudoso, así como otras …
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The clinical utility of tissue polymerase chain reaction, tissue culture, and tissue histology in blood-culture negative infective endocarditis - a South African single hospital experience
… had serum serology for Bartonella spp. and Coxiella spp. performed, 5/11 (45.5%) were positive for Bartonella spp. There was a 100% concordance rate between positive serum serology and tissue PCR. Tissue PCR impacted the antimicrobial regimen in 20/27 (74%) cases. Tissue culture and tissue …
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A Metagenomic Study of The Tick Midgut
… the <em>Rickettsia</em> spp. and <em>Coxiella</em> spp., that are commonly found in ticks were confirmed, as well as some highly prevalent genera that were previously undocumented. Furthermore, multiple pathogenic genera sequences were often found in the same tick, suggesting the …