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Showing 1 to 2 of 2 for “"Coupled Gating"”.

  1. THE ROLE OF ATP AND FK-506 BINDING PROTEIN IN THE COUPLED GATING OF SKELETAL RYANODINE RECEPTORS

    Neumann, Jacob Trevor

    … and central core disease. Therefore, investigating the mechanisms that control RyR1 function can help identify how these mutations cause deleterious Ca<super>2+</super> handling. Currently, most published research on RyR1s gating utilizes single RyR1 reconstituted into planar lipid bilayers …

    siu-theses Repository record

  2. Untersuchung einer Calcineurin-bindungsdefizienten FKBP12.6-Mutante in Kardiomyozyten

    Kania, Astrid2012

    … koordiniertere Öffnung benachbarter RyR (coupled gating) bedingt zudem eine verbesserte relative Zellverkürzung der Zelle. Da die genaue Anzahl bzw. Funktion aller Bindungspartner am RyR derzeit noch nicht abschließend geklärt ist, liegt die Vermutung nahe, dass die Wirkung von FKBP durch …

    goettingen Repository record