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Showing 1 to 20 of 26 for “"Cosolvent"”.
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Spectroscopic and thermodynamic studies of supercritical fluid solutions containing a cosolvent
The addition of a cosolvent to a supercritical fluid (SCF) can alter the properties of the solvent to enhance both solubilities and selectivities for particular solutes through a variety of specific and non-specific interactions. Although many cosolvent effects have traditionally been explained in …
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Removal of polymer coating with supercritical carbon dioxide
… were also developed to calculate HSP's for cosolvents and polymers. With the solvent, cosolvent, and polymer thus fully characterized in terms of the HSP values, the systems are then analyzed in terms of the like and unlike (solvent/polymer, cosolvent/polymer, and solvent/cosolvent) binary …
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Volumetric Properties and Viscosity of Fluid Mixtures at High Pressures: Lubricants and Ionic Liquids
… used in lubricants and ionic liquids, with cosolvent addition, for use in biomass and polymer processing. Experimental density data were collected using a variable-volume view-cell at pressures up to 40 MPa and temperatures up to 398 K. A unique high pressure rotational viscometer was …
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Photocrosslinkable polyimide and poly(imide siloxane) homo- and copolymers: synthesis and characterization
… end blocked polydimethyl siloxane oligomers in a cosolvent system of tetrahydrofuran and N-methyl-2-pyrrolidinone. These dysfunctional aminopropyl terminated siloxane oligomers were prepared through an anionic ring opening equilibration polymerization of octamethylcyclotetrasiloxane with …
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Developments and applications of methods for palladium- and copper-catalyzed carbon-nitrogen bond formation
… 3). Part I. Chapter 1. Use of a "Catalytic" Cosolvent, N,N-Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch A general, efficient method for C-N cross-coupling has been developed using N,N-dimethyloctanamide as a cosolvent for biphasic continuous-flow …
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Preparação e caracterização de complexos multicomponentes contendo ciclodextrinas e benznidazol
… and 1-methyl-2-pyrrolidone showed an action cosolvent (both solvents) and complexing (1-methyl-2-pyrrolidone). The best results were obtained with complexes involving 1-methyl-2-pyrrolidone and hydroxypropylbeta- cyclodextrin, with an increased of benznidazole solubility in 27.9 and 9.4 …
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Siloxane modified engineering polymers: synthesis and characteristics
… oligomers were quantitatively reacted in a cosolvent system. The poly(amic acid) intermediates were then cyclodehydrated employing two different thermal treatments to afford the imidized homo- and copolymers. The first imidization process, conducted on solution cast poly(amic acid) films, …
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Development and characterization of next generation batteries
… and the effect of adding hydrofluoroether (HFE) cosolvent on the cycling performance of Li−S battery is discussed. In order to evaluate interactions that might change Li−S battery properties, four different HFEs with varying degrees of fluorination were examined as cosolvents in the …
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Study of Moisture and Water Effects in Low Temperature Crystallization of Perovskite Film for Efficient Solar Cells
… hysteresis in the devices. Use of water as cosolvent improved the film morphology, but adding up to 25 vol. % water in the precursor solution does not significantly affect the power conversion efficiency. Future work on understanding the crystallization process under varying humidity levels …
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Preparation and Evaluation of Oil-in-Water Self-Nanoemulsifying Systems with Potential for Pulmonary Delivery
… (SNEDDS) are mixtures of oil, surfactant and cosolvent/cosurfactant, which emulsify under conditions of gentle agitation. SNEDDS can drastically improve absorption of poorly water soluble drugs by keeping it in solubilized form at the site of absorption. The objective of the study was to …
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Palladium reagents for bioconjugation
… and physiologically relevant conditions. The cosolvent-free aqueous conditions were applied to the conjugation of a variety of biomolecules with affinity tags, heterocycles, fluorophores, and functional handles. Additionally, bispalladium reagents were used to perform macrocyclization of …
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Biopharmaceutical approaches for improved drug delivery across ocular barriers
… in comparison to the solution formulations (cosolvent and HPβCD based) tested. </p> <p>Furthermore, for the first time, studies in anesthetized male New Zealand rabbits demonstrate that topically applied P-gp inhibitors can diffuse to the RPE and alter the elimination kinetics of a …
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THERMODYNAMIC PROPERTIES OF THE UNFOLDED ENSEMBLE OF PROTEINS
… residues of the protein with the solvent and the cosolvent (direct interactions), and the properties of the solution itself (indirect interactions) are together critical to the unfolded chain's properties and have been quantitatively estimated. Unfolded, protonated BBL can be refolded by tuning …
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The rational design of dermatological formulations
… determined and demonstrated how the addition of cosolvent could impact upon the permeation of the two weak acids by altering the ionisation state of the permeants. The cosolvents, (typical formulation excipients) were water, propylene glycol ethanol, mineral oil, miglyol and Transcutol . To begin …
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Structure-property behavior of elastomeric telechelic ionomers in bulk and solution
… equilibrium between the ionic groups, the polar cosolvent, and the nonpolar solvent. More concentrated solutions or gels in nonpolar solvents display a unique viscoelastic behavior which is very dependent upon architecture, molecular weight, and neutralizing cation. Solutions of ionomers (5 g/dl) …
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Development of Novel Methodologies for the Electrodeposition of Polypyrrole-based Films in Controlled Morphologies with Potential Application in Nitrate Sensing.
… procedure was developed using an emulsion in a cosolvent mixture. Adsorbed toluene droplets were employed as soft templates to direct polymer growth. The microstructures only grew in the presence of both ClO4 - and H2PO4 - doping ions, due to a slower rate of polymer propagation in this …
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Preformulation and Formulation Development of a Novel Radioprotectant Drug
… can be enhanced by increasing the pH, by using cosolvent systems, and by complexation agents like cyclodextran. A suspension formulation was developed using 0.1M Potassium phosphate monobasic, 1% Tween 80 and 0.15M sodium chloride. The stability data of the drug indicates that there is less than …
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