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Showing 1 to 20 of 45 for “"Corynebacterium glutamicum"”.
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Transcriptional regulation in Corynebacterium glutamicum
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1996.
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Nitrogen metabolism in Corynebacterium glutamicum ATCC 13032
Corynebacterium glutamicum is extensively used for the commercial production of a host of amino acids including lysine, glutamate, and threonine. Consequently, much research has been directed at analyzing nitrogen metabolism in this bacterium. In particular, our research focused on investigating …
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Glycogen metabolism in Corynebacterium glutamicum ATCC 13032
Corynebacterium glutamicum is a Gram-positive facultative aerobe particularly known for its industrial application in the synthesis of amino acids, such as L-glutamate and Llysine. The central metabolic pathways of this organism has been an area of much research by many groups. Linked to glycolysis …
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Untersuchungen zur L-Serin-Bildung mit Corynebacterium glutamicum
… with a central position in the metabolism of corynebacterium glutamicum. This is especially because of the reaction catalyzed by the serine hydroxymethyltransferase (SHMT) in which serine is degraded to glycine and a C1 unit. It was an aim of this work to analyze the formation of the …
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L-arginine overproduction in Corynebacterium glutamicum ATCC 13032
Corynebacterium glutamicum is widely used for the commercial production of a variety of amino acids, including L-lysine, L-glutamate and L-threonine. With the exception of Larginine, the biosynthesis and regulation of most of these compounds in this bacterium are relatively well characterised in …
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The genetics of mycolic acids biosynthesis in Corynebacterium glutamicum
Corynebacterium glutamicum and Brevibacterium are of great importance to the fermentation industry. They have potential for application in foreign protein expression. This research has been focused mainly on strain improvement and development of technique to overcome the barriers that effect …
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Metabolic engineering of amino acid production in Corynebacterium glutamicum
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1995.
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Untersuchung des Argininmetabolismus und dessen Regulation in Corynebacterium glutamicum ATCC 13032
… von großem wirtschaftlichem Interesse. In Corynebacterium glutamicum, einem industriell bedeutsamen Produzenten von Aminosäuren, gibt es ein Argininoperon, welches aus den Genen argCJBDFRGH besteht und dessen Transkription ausgehend von einem Promotor stromaufwärts von argC durch ein …
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Investigation of carbon fluxes in central metabolic pathways of Corynebacterium glutamicum
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1996.
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Branchpoint flux analysis in the L-lysine pathway of Corynebacterium glutamicum
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1997.
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DNA technology for Corynebacterium glutamicum : isolation and characterization of amino acid biosynthetic genes
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Applied Biological Sciences, 1989.
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Modeling based process development of fed-batch bioprocesses: L-valine production by Corynebacterium glutamicum
… L-valine production by a genetically modified C. glutamicum. With four experiments, a model was developed and selected. Two different model discriminating criteria were used for the design of these experiments. The selected model was used for calculation of optimal feed trajectories for …
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Design, manufacture, and application of DNA microarrays to study gene expression phenotypes of lysine-producing Corynebacterium glutamicum
Corynebacterium glutamicum partial genome DNA microarrays were constructed that were capable of assaying the transcriptional profile of the genes of pathways involved in central carbon metabolism and lysine biosynthesis. It was found that to ensure arrays of high quality, protocols applying the …
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Development and application of a microfluidic single-cell cultivation device to simulate dynamic environmental conditions for Corynebacterium glutamicum
… used, biotechnologically relevant bacterium *Corynebacterium glutamicum* was used to investigate the influence of different fluctuating environmental conditions on its growth and morphology. An initial study of nutrient oscillations with intervals between 10 seconds and 1 hour showed …
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Identification and characterisation of the cell surface and enzymatic barriers to plasmid transformation in Corynebacterium glutamicum and related species
Non-pathogenic corynebacteria including Corynebacterium glutamicum, Brevibacterium flavum, and B. lactofermentum have been used traditionally for industrial production of amino acids. Recently, these strains have been also studied using molecular biology or recombinant DNA approaches. However, a …
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A streamlined Workflow for Transposon Mutagenesis in Corynebacterium glutamicum Based on Third-Generation Sequencing and its Application for Advanced Genetic Screens
… the prophage- and insertion sequence(IS)-free *Corynebacterium glutamicum* platform strain CR101 for an efficient integration system, a transposon mutagenesis system based on the endogenous IS*Cg1* transposase and a streamlined workflow for transposon mutant library preparation and sequencing …
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