Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 13 of 13 for “"Corticotropin-releasing factor (CRF)"”.
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Effects of nicotine on content of corticotropin releasing factor (CRF) in rat amygdala, hypothalamus and brain stem
… on hypothalamic and extra hypothalamic levels of corticotropin releasing factor (CRF) were examined in 104 rats. CRF, a 41-amino acid peptide involved in responses to stress, fear and anxiety, influences the same neurotransmitter systems as nicotine, a psychoactive component of tobacco. …
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Corticotropin-releasing factor and acute post-operative gut function in truamatic abdominal injury and elective abdominal surgery
… axis. The response is activated under stress by corticotropin-releasing factor (CRF), the well-known 41 amino acid peptide neuro-hormone. Evidence from animal and human studies suggests that peripheral CRF is present in the gastrointestinal tract and associated with inflammatory changes. …
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Satiety induced by neuropeptide FF and gastrin in birds
… melanin-concentrating hormone mRNA in the LH and corticotropin-releasing factor (CRF) mRNA in the PVN, suggesting that CRF signaling was involved in the hypothalamic response to gastrin. However, co-injection of gastrin and astressin, a CRF receptor antagonist did not affect gastrin-induced …
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INVESTIGATING THE FUNCTIONAL ROLES OF CRF-BINDING PROTEIN HOMOLOGUE IN THE RESPONSE TO PHYSIOLOGICAL STRESSES IN DROSOPHILA
… responses in all animals. The mammalian hormone, corticotropin-releasing factor (CRF), coordinates these stress responses to a variety of different stresses. CRF has three binding partners, including two receptors and a binding protein, and it is the receptors that initiate signaling pathways …
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Studies on the mode of CRF action in the optic tectum of the African Clawed Frog, Xenopus laevis
… capture tradeoffs. The neuropeptide corticotropin releasing factor (CRF) modulates discrete aspects of prey capture and predator avoidance, but the mechanisms underlying this modulation are unknown. This dissertation consists of my research exploring two potential pathways that can …
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Social isolation enhances calcium signaling and synaptic plasticity in dopamine neurons of the ventral tegmental area
… Ca²⁺ signaling and synaptic plasticity. Although corticotropin releasing factor (CRF) further facilitates mGluR/IP3-mediated Ca²⁺ signaling in DA neurons, alterations in CRF receptors are not responsible for the effects of isolation on Ca²⁺ signaling and synaptic plasticity. In addition, the …
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Stress, Monoamines, and Cognitive Flexibility
… cortex (PFC). The stress-related neuropeptide, corticotropin-releasing factor (CRF) regulates monoamine systems that project to the PFC, including the locus coeruleus norepinephrine (LC-NE) system and the dorsal raphe-serotonin (DRN-5-HT) system. CRF actions on these systems may underlie …
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Molecular and cellular mechanisms of energy homeostasis in birds
… domain protein 2 in the promoter of corticotropin-releasing factor (CRF) because of hypomethylation in one CpG site at its core binding site in stressed LWS, which explains the increased CRF expression in the paraventricular nucleus of the hypothalamus. We next determined effects of …
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Stress-induced relapse to cocaine seeking in the rat : contributions of central nervous system corticotropin-releasing factor and noradrenaline
… the role of two neurobiological systems, corticotropin-releasing factor (CRF) and noradrenaline (NE), in stress- and cocaine-induced relapse to cocaine seeking, using an animal model of relapse. Rats were allowed to self-administer cocaine (0.5 or 1.0 mg/kg/infusion, i.v.) for 3 hours …
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Neurotransmitter Modulation of Alcohol-Induced GABAergic Signaling in the Central Amygdala
… Neurotransmitter systems such as oxytocin (OXT), corticotropin-releasing factor (CRF), and serotonin (5-HT) have demonstrated therapeutic potential in reducing alcohol-related behaviors. However, how these neuromodulators alter GABAergic transmission in the CeA and interact with alcohol, …
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Alterazioni indotte dall'isolamento sociale sulla regolazione a feedback negativo dell'asse ipotalamo-ipofisi-surrene
… isolation results in a decrease in plasma adrenocorticotropin (ACTH) and corticosterone levels and in a decrease in the brain and plasma concentrations of neuroactive steroids that act as positive modulators at GABAA receptors. Moreover, social deprivation is accompanied by an enhanced …
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Mechanisms of hypothalamic regulation of food intake in birds
… stress, and expression of several anorexigenic factors was up-regulated including corticotropin-releasing factor (CRF), CRF receptor sub-types 1 and 2 (CRFR1 and CRFR2, respectively), melanocortin receptor 4, and urocortin 3, suggesting that stress-induced anorexia in the LWS may result from …
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Role of Histamine, and Its Interaction With Corticotropin Releasing Factor and Bombesin in Food Intake Regulation of Chickens
… the role of histamine, and its interaction with corticotropin releasing factor (CRF) and bombesin (BM) in food intake regulation of chickens. The hypothesis being tested was as follows: One component of the neuroregulation of food intake involves histaminergic activity in the hypothalamus, acting …