Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Cortical migration"”.
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Organization principles of the early Drosophila embryo
… the Histone Locus Body size control and cortical migration of nuclei. The Histone Locus Body (HLB) is an evolutionarily conserved nuclear body that regulates the transcription and processing of histone mRNAs. We show that Drosophila HLBs form through phase separation. During …
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Generation of focal Depdc5 knockout mouse model and implications for focal epilepsy
… familial focal epilepsy and malformations of cortical development. It is also associated with an increased risk of Sudden-Unexplained Death in Epilepsy (SUDEP). It remains unknown whether seizures due to DEPDC5 loss are a result of in utero cortical developmental defects or later neuronal …
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Linking WRP/srGAP3 to the Cognitive Deficits in 3p- Syndrome and Its Role in the Regulation of Dendritic Filopodia Formation
… domain of unknown function and to regulate cortical migration in developing neurons. This study focuses on the regulatory capacity of WRP during the development of neuronal connections in the central nervous system, and what role its loss may have on cognitive functions.</p><p>To assess …